Evidence map›Paper›PMID 30338997›Full record

ArticleJournal of the American Chemical Society2018

Determining Cholesterol Binding to Membrane Proteins by Cholesterol

Matthew R Elkins, Ivan V Sergeyev, Mei Hong

Open access · greenAbstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 40 papers.

0numbers the graph read from it
0cells of the map it votes in
40citing papers in PubMed
2.3field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

40 citing papers in PubMed, 73 citations in OpenAlex.

  1. Article
  2. Article
  3. Review
  4. Review
  5. Article
  6. Solid-State NMR of Virus Membrane Proteins.Accounts of chemical research · 2025
    Article
  7. Article
  8. Direct observation of cholesterol monohydrate crystallization.Proceedings of the National Academy of Sciences of the United States of America · 2025
    Article
  9. The Role of Cholesterol in M2 Clustering and Viral Budding Explained.Journal of chemical theory and computation · 2025
    Article
  10. Review
  11. Review
  12. Article
  13. Characterization of dielectric properties and their impact on MAS-DNP NMR applications.Journal of magnetic resonance (San Diego, Calif. : 1997) · 2024
    Article
  14. Article
  15. Article
  16. Segmental Dynamics of Membranous Cholesterol are Coupled.Journal of the American Chemical Society · 2023
    Article
  17. Article
  18. Specific Lipid Studies in Complex Membranes by Solid-State NMR Spectroscopy.Chemistry (Weinheim an der Bergstrasse, Germany) · 2022
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 1 country.

Matthew R ElkinsDepartment of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.
Ivan V SergeyevBruker Biospin , 15 Fortune Drive , Billerica , Massachusetts 01821 , United States.
Mei HongDepartment of Chemistry , Massachusetts Institute of Technology , Cambridge , Massachusetts 02139 , United States.ORCID 0000-0001-5255-5858
Massachusetts Institute of Technology · USBruker (United States) · US

Funding

Structures and Dynamics of Proton and Cation-Dependent Channels and TransportersR01GM088204 · NIGMS · MASSACHUSETTS INSTITUTE OF TECHNOLOGY · PI HONG, MEI · 2009 to 2024
$4.8M
NIGMS NIH HHS R01 GM088204
6 · The paper itself

Abstract

We present a general strategy for determining the cholesterol-binding site of eukaryotic membrane proteins in native-like lipid membranes by NMR spectroscopy. The strategy combines yeast biosynthetic

Indexed as

Nuclear Magnetic Resonance, BiomolecularBinding SitesCarbon IsotopesCholesterolMembrane ProteinsMolecular ConformationMolecular Docking SimulationSaccharomyces cerevisiaeCarbon-13Carbon IsotopesCholesterolMembrane Proteins

Identifiers

PMID30338997
PMCPMC6361393
OpenAlexW2896686597

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.