Evidence map›Paper›PMID 30338752›Full record

ReviewMicrobiology spectrum2018

Biology of Oral Streptococci.

J Abranches, L Zeng, J K Kajfasz, S R Palmer, B Chakraborty, Z T Wen, V P Richards, L J Brady, J A Lemos

Registry-linked trialOpen access · greenAbstract readReview
In one paragraph

Review in Microbiology spectrum, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT04295525 (PHoral), which is not on this map. Cited by 332 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
332citing papers in PubMed, 4 pooled it
32.6field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT04295525 naunknown statusnot on this mapstarted 2022, after this paper: background citation

PHoral: Effects of Carnosine Supplementation on Quantity/Quality of Oral Salivae in Healthy Volunteer and in Subjects Affected by Common Oral Pathologies.

TypeinterventionalSponsorUniversity of MilanRan2022 to 2022Enrolled60ConditionsOral DiseasesArms400 mg mucoadhesive oral tablet, placebo mucoadhesive oral tablet
3 · Its place in the literature

Who cites it

332 citing papers in PubMed, 4 syntheses or guidelines pooled it, 521 citations in OpenAlex.

  1. Pooled it
  2. The prevalence of oral mucositis after radiotherapy in patients with Head and Neck Cancer and its associated factors: a meta-analysis.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2025
    Pooled it
  3. Pooled it
  4. Pooled it
  5. Trial
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  8. Article
  9. Establishment of anmSystems · 2026
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  11. Review
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  18. TheApplied and environmental microbiology · 2026
    Article
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272 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 5 institutions in 1 country.

J AbranchesDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
L ZengDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
J K KajfaszDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
S R PalmerDivision of Biosciences, College of Dentistry, Ohio State University, Columbus, OH.
B ChakrabortyDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
Z T WenDepartment of Comprehensive Dentistry and Biomaterials and Department of Microbiology, Immunology and Parasitology, Louisiana State University Health Sciences Center, New Orleans, LA.
V P RichardsDepartment of Biological Sciences, Clemson University, Clemson, SC.
L J BradyDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
J A LemosDepartment of Oral Biology, University of Florida College of Dentistry, Gainesville, FL.
Florida College · USUniversity of Florida · USClemson University · USLouisiana State University Health Sciences Center New Orleans · USThe Ohio State University · US

Funding

MEMBRANES OF THE DENTAL PATHOGEN STREPTOCOCCUS MUTANSR01DE008007 · NIDCR · UNIVERSITY OF FLORIDA · PI L. Jeannine Brady, Surabhi Mishra · 1986 to 2026
$8.6M
GENE REGULATION AND PHYSIOLOGY OF STREPTOCOCCUS MUTANSR01DE012236 · NIDCR · UNIVERSITY OF ROCHESTER · PI Lin Zeng · 1997 to 2026
$8.5M
BrpA in Virulence Modulation of Streptococcus mutansR01DE019452 · NIDCR · LSU HEALTH SCIENCES CENTER · PI ZEZHANG TOM WEN, Hui Wu · 2009 to 2026
$6.3M
Intracellular Invasion by Streptococcus mutans: Significance in DiseaseR01DE022559 · NIDCR · UNIVERSITY OF ROCHESTER · PI Jacqueline Abranches, Christine M. Szymanski · 2013 to 2026
$4.8M
Role of the Spx Regulator in Streptococcus mutansR01DE019783 · NIDCR · UNIVERSITY OF ROCHESTER · PI LEMOS, JOSE A · 2010 to 2020
$3.7M
Functional Amyloid Formation in Streptococcus mutansR01DE021789 · NIDCR · UNIVERSITY OF FLORIDA · PI BRADY, L. JEANNINE, LONG, JOANNA R · 2012 to 2021
$3.7M
Functional amyloid formation in streptococcus mutansR56DE021789 · NIDCR · UNIVERSITY OF FLORIDA · PI BRADY, L. JEANNINE, LONG, JOANNA R · 2024 to 2024
$506k
eDNA Secretion and eDNA-Cell Interactions in Biofilm FormationR21DE025348 · NIDCR · LSU HEALTH SCIENCES CENTER · PI BRADY, L. JEANNINE, WEN, ZEZHANG TOM · 2016 to 2017
$419k
NIAID NIH HHS HHSN272200900007CNIDCR NIH HHS R01 DE008007NIDCR NIH HHS R01 DE012236NIDCR NIH HHS R01 DE019452NIDCR NIH HHS R01 DE019783NIDCR NIH HHS R01 DE021789NIDCR NIH HHS R01 DE022559NIDCR NIH HHS R21 DE025348NIDCR NIH HHS R56 DE021789
6 · The paper itself

Abstract

Bacteria belonging to the genus

Indexed as

Carbohydrate MetabolismDental CariesEndocarditisFermentationHumansHydrogen PeroxideMetagenomicsMicrobiotaMouthPhylogenyStreptococcusStreptococcus gordoniiStreptococcus mutansStreptococcus salivariusHydrogen Peroxide

Identifiers

PMID30338752
PMCPMC6287261
OpenAlexW2896937938

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.