Evidence map›Paper›PMID 30338741›Full record

ArticleCurrent HIV research2018

Prevalence of HIV in Patients with Malignancy and of Malignancy in HIV Patients in a Tertiary Care Center from North India.

Sanjeev Sinha, Ashish Agarwal, Kartik Gupta, Dibyakanti Mandal, Mitul Jain, Roger Detels, Karabi Nandy, Michelle A DeVos, S K Sharma, N Manoharan and 4 more

Open access · hybridAbstract read
In one paragraph

Article in Current HIV research, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.4field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 9 citations in OpenAlex.

  1. Review
  2. HIV/AIDS Associated Lymphoma: Review.Blood and lymphatic cancer : targets and therapy · 2022
    Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 2 countries.

Sanjeev SinhaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Ashish AgarwalDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Kartik GuptaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Dibyakanti MandalDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Mitul JainDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
Roger DetelsDepartment of Epidemiology, UCLA School of Public Health, Los Angeles, CA, United States.
Karabi NandyDepartment of Biostatistics and Epidemiology, School of Public Health, University of North Texas Health Science Center, United States.
Michelle A DeVosDepartment of Biostatistics and Epidemiology, School of Public Health, University of North Texas Health Science Center, United States.
S K SharmaDepartment of Medicine, All India Institute of Medical Sciences, New Delhi, India.
N ManoharanDepartment of Radiation Oncology, Dr. BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
P K JulkaDepartment of Radiation Oncology, Dr. BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
G K RathDepartment of Radiation Oncology, Dr. BRA IRCH, All India Institute of Medical Sciences, New Delhi, India.
Richard F AmbinderDivision of Hematologic Malignancies, The Johns Hopkins University School of Medicine, Baltimore, Maryland, United States.
Ronald T MitsuyasuDepartment of Medicine, UCLA CARE Center, David Geffen School of Medicine at UCLA, Los Angeles, CA, United States.
All India Institute of Medical Sciences · INUniversity of North Texas Health Science Center · USJohns Hopkins University · USUCLA Health · US

Funding

UCLA Rapid, Relevant, Rigorous Implementation Science HubP30MH058107 · NIMH · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI Nina Thawata Harawa · 1997 to 2026
$53.5M
Studies on the Prevalence, Risk Factors and Outcomes of Cancers in HIV in IndiaR21CA177310 · NCI · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI MITSUYASU, RONALD T. · 2013 to 2014
$320k
NCI NIH HHS R21 CA177310NIMH NIH HHS P30 MH058107
6 · The paper itself

Abstract

BACKGROUND AND

objectivesPeople living with HIV/AIDS are at an increased risk of developing cancer. The goals of this study were to obtain data on the prevalence of HIV in the cancer population and vice versa at a major tertiary cancer and HIV center in North India.

methodsThis cross-sectional study was conducted over a 3-year period from July 2013 to June 2016, wherein successive HIV positive patients from an anti-retroviral therapy (ART) center were screened for malignancy. Simultaneously, successive cancer patients at the cancer center were screened for HIV. Baseline demographic details, risk factors, and laboratory investigations were obtained for all the patients.

resultsAmong the 999 HIV-positive patients at the ART center, the prevalence of malignancy was 2% (n=20; 95% confidence interval (CI) 1.13, 2.87). Among the 998 patients with a malignancy, the prevalence of HIV infection was 0.9% (n=9; 95% CI 0.31, 1.49). Weight loss, loss of appetite, and fever were the most common symptoms in patients with HIV and cancer. Among 29 patients with HIV and cancer, AIDS-defining cancer was found in 19 patients; non-Hodgkin's lymphoma was the most common malignancy reported (n=13). INTERPRETATION AND

conclusionThere is a low prevalence of HIV in cancer patients as well as a low prevalence of cancer in HIV patients. AIDS-defining cancers remain much more common than non-AIDS-defining cancers. With the increased coverage of ART, it is expected that non-AIDSdefining cancers will increase, as is evident from data from more developed countries.

Indexed as

AdultAgedCross-Sectional StudiesFemaleHIV InfectionsHumansIndiaMaleMiddle AgedNeoplasmsPrevalenceRisk FactorsTertiary Care CentersAIDS-defining cancerARTcancerHIVinvasive cervical cancernon-Hodgkin's lymphoma.

Identifiers

PMID30338741
PMCPMC6416457
OpenAlexW2896332768

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.