Evidence map›Paper›PMID 30338166›Full record

ArticleBiomedical optics express2018

Wearable speckle plethysmography (SPG) for characterizing microvascular flow and resistance.

Michael Ghijsen, Tyler B Rice, Bruce Yang, Sean M White, Bruce J Tromberg

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 27 papers.

0numbers the graph read from it
0cells of the map it votes in
27citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

27 citing papers in PubMed.

  1. Article
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  3. Review
  4. Article
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. The 2023 wearable photoplethysmography roadmap.Physiological measurement · 2023
    Review
  12. Article
  13. Article
  14. Article
  15. Article
  16. Review
  17. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Michael GhijsenLaser Microbeam and Medical Program, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, CA 92612, USA.
Tyler B RiceLaser Associated Sciences Inc., 16 Foxglove Way, Irvine, CA 92612, USA.
Bruce YangLaser Associated Sciences Inc., 16 Foxglove Way, Irvine, CA 92612, USA.
Sean M WhiteLaser Associated Sciences Inc., 16 Foxglove Way, Irvine, CA 92612, USA.
Bruce J TrombergLaser Microbeam and Medical Program, Beckman Laser Institute, 1002 Health Sciences Road, Irvine, CA 92612, USA.

Funding

University of California Health Participation in the National COVID Cohort Collaborative (N3C)UL1TR001414 · NCATS · UNIVERSITY OF CALIFORNIA-IRVINE · PI COOPER, DAN M, VILAIN, ERIC J. · 2015 to 2023
$35.1M
MEDICAL SCIENTIST TRAINING PROGRAMT32GM008620 · NIGMS · UNIVERSITY OF CALIFORNIA-IRVINE · PI GOLDIN, ALAN L · 1999 to 2023
$8.1M
Virtual Photonocs TechnologiesP41EB015890 · NIBIB · UNIVERSITY OF CALIFORNIA-IRVINE · PI DURKIN, ANTHONY J · 2012 to 2017
$7.0M
Improved pulse oximetry performance using transmission optical flowmetry.R43GM122132 · NIGMS · LASER ASSOCIATED SCIENCES, INC. · PI RICE, TYLER · 2017 to 2017
$149k
Quantitative Optical Metabolic Imaging of Peripheral Arterial DiseaseF30HL132481 · NHLBI · UNIVERSITY OF CALIFORNIA-IRVINE · PI GHIJSEN, MICHAEL · 2016 to 2018
$109k
NCATS NIH HHS UL1 TR001414NHLBI NIH HHS F30 HL132481NIBIB NIH HHS P41 EB015890NIGMS NIH HHS R43 GM122132NIGMS NIH HHS T32 GM008620
6 · The paper itself

Abstract

In this work we introduce a modified form of laser speckle imaging (LSI) referred to as affixed transmission speckle analysis (ATSA) that uses a single coherent light source to probe two physiological signals: one related to pulsatile vascular expansion (classically known as the photoplethysmographic (PPG) waveform) and one related to pulsatile vascular blood flow (named here the speckle plethysmographic (SPG) waveform). The PPG signal is determined by recording intensity fluctuations, and the SPG signal is determined via the LSI dynamic light scattering technique. These two co-registered signals are obtained by transilluminating a single digit (e.g. finger) which produces quasi-periodic waveforms derived from the cardiac cycle. Because PPG and SPG waveforms probe vascular expansion and flow, respectively, in cm-thick tissue, these complementary phenomena are offset in time and have rich dynamic features. We characterize the timing offset and harmonic content of the waveforms in 16 human subjects and demonstrate physiologic relevance for assessing microvascular flow and resistance.

Indexed as

(170.0170) Medical optics and biotechnology(170.3890) Medical optics instrumentation(230.0230) Optical devices

Identifiers

PMID30338166
PMCPMC6191642

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.