ArticleBiomedical optics express2018
Quantitative second harmonic generation microscopy for the structural characterization of capsular collagen in thyroid neoplasms.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 26 papers.
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Who cites it
26 citing papers in PubMed, 50 citations in OpenAlex.
- Association of tumor associated collagen signature with lymph node metastasis in pancreatic ductal adenocarcinoma.Bioengineering & translational medicine · 2026Article
- Quantitative second harmonic generation microscopy for characterizing collagen remodeling in papillary thyroid carcinoma.Journal of biomedical optics · 2026Article
- Correlative multimodal imaging for microscale spatial mapping of collagen-gene activity interactions in human tissues.Npj imaging · 2026Article
- Improving Non-Invasive Prediction of Thyroid Nodule Malignancy: A Machine Learning-Based Clinical Approach.Cancer management and research · 2026Article
- Polarization-Interference Jones Matrix Sensors of Layer-by-Layer Scanning of Polycrystalline Dehydrated Blood Films. Fundamental and Applied Aspects.Sensors (Basel, Switzerland) · 2025Article
- Quantitative image analysis of the extracellular matrix of esophageal squamous cell carcinoma and high grade dysplasia via two-photon microscopy.Scientific reports · 2025Article
- Multitask machine learning-based tumor-associated collagen signatures predict peritoneal recurrence and disease-free survival in gastric cancer.Gastric cancer : official journal of the International Gastric Cancer Association and the Japanese Gastric Cancer Association · 2024Article
- Widefield polarization-resolved second harmonic generation imaging of entire thyroid nodule sections for the detection of capsular invasion.Biomedical optics express · 2024Article
- Structural changes in the crystalline lens as a function of the postmortem interval assessed with two-photon imaging microscopy.Biomedical optics express · 2024Article
- Investigating cartilage-related diseases by polarization-resolved second harmonic generation (P-SHG) imaging.APL bioengineering · 2024Article
- Imaging of colorectal adenomas with pseudoinvasion and malignant polyps using two-photon excitation microscopy.Frontiers in oncology · 2024Article
- Differential diagnosis of thyroid nodule capsules using random forest guided selection of image features.Scientific reports · 2022Article
- Identification of the collagen family as prognostic biomarkers in papillary thyroid carcinoma.Endocrine · 2022Article
- Kinetics and Mechanisms ofBioengineering (Basel, Switzerland) · 2022Article
- PSHG-TISS: A collection of polarization-resolved second harmonic generation microscopy images of fixed tissues.Scientific data · 2022Article
- Assessment of Ultra-Early-Stage Liver Fibrosis in Human Non-Alcoholic Fatty Liver Disease by Second-Harmonic Generation Microscopy.International journal of molecular sciences · 2022Article
- Assessment of Extramammary Paget Disease by Two-Photon Microscopy.Frontiers in medicine · 2022Article
- Computer-assisted quantification of tumor-associated collagen signatures to improve the prognosis prediction of breast cancer.BMC medicine · 2021Article
- Association of Tumor-Associated Collagen Signature With Prognosis and Adjuvant Chemotherapy Benefits in Patients With Gastric Cancer.JAMA network open · 2021Article
- Nomogram model combining macro and micro tumor-associated collagen signatures obtained from multiphoton images to predict the histologic grade in breast cancer.Biomedical optics express · 2021Article
Corrections and comments
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Authors and funding
7 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Quantitative second harmonic generation microscopy was used to investigate collagen organization in the fibrillar capsules of human benign and malignant thyroid nodules. We demonstrate that the combination of texture analysis and second harmonic generation images of collagen can be used to differentiate between capsules surrounding the thyroid follicular adenoma and papillary carcinoma nodules. Our findings indicate that second harmonic generation microscopy can provide quantitative information about the collagenous capsule surrounding both the thyroid and thyroid nodules, which may complement traditional histopathological examination.
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