Evidence map›Paper›PMID 30338156›Full record

ArticleBiomedical optics express2018

Quantitative diffuse reflectance spectroscopy of short-term changes in tumor oxygenation after radiation in a matched model of radiation resistance.

Paola Monterroso Diaz, Samir V Jenkins, Kinan Alhallak, Daria Semeniak, Robert J Griffin, Ruud P M Dings, Narasimhan Rajaram

Abstract read
In one paragraph

Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

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  20. Non-contact optical spectroscopy for metabolic and vascular characterizations of orthotopic tongue cancer modelsIEEE journal of selected topics in quantum electronics : a publication of the IEEE Lasers and Electro-optics Society
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Paola Monterroso DiazDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Samir V JenkinsDivision of Radiation Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Kinan AlhallakDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Daria SemeniakDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.
Robert J GriffinDivision of Radiation Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Ruud P M DingsDivision of Radiation Biology, University of Arkansas for Medical Sciences, Little Rock, AR 72205, USA.
Narasimhan RajaramDepartment of Biomedical Engineering, University of Arkansas, Fayetteville, AR 72701, USA.

Funding

Study of the Cell-specific Inflammasome Responses During Defense Against Gram-negative BacteriaP20GM103625 · NIGMS · UNIV OF ARKANSAS FOR MED SCIS · PI SMELTZER, MARK S · 2012 to 2021
$21.5M
NIGMS NIH HHS P20 GM103625
6 · The paper itself

Abstract

There is a critical need to identify patients with radiation-resistant tumors early after treatment commencement. In this study, we use diffuse reflectance spectroscopy (DRS) to investigate changes in vascular oxygenation and total hemoglobin concentration in A549 radiation-sensitive and resistant tumors treated with a clinically relevant dose fraction of 2 Gy. DRS spectra were acquired before, immediately after, 24, and 48 hours after radiation. Our data reveals a significantly higher reoxygenation (sO

Identifiers

PMID30338156
PMCPMC6191608

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.