ArticleBiomedical optics express2018
Visualizing the 3D cytoarchitecture of the human cochlea in an intact temporal bone using synchrotron radiation phase contrast imaging.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
32 citing papers in PubMed, 49 citations in OpenAlex.
- IE-Map: a novel in-vivo atlas and template of the human inner ear.Scientific reports · 2021Trial
- The cochlear morphometry compendium: High-resolution synchrotron measurements and normative reference values.Journal of anatomy · 2026Article
- High resolution, contrast-enhanced X-ray microscopy of theFrontiers in neuroscience · 2026Article
- The State of High-Resolution Imaging of the Human Inner Ear: A Look Into the Black Box.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025Review
- Application of Synchrotron Radiation in Fundamental Research and Clinical Medicine.Biomedicines · 2025Review
- Article
- Muscle structure assessment using synchrotron radiation X-ray micro-computed tomography in murine with cerebral ischemia.Scientific reports · 2024Article
- Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy.The Laryngoscope · 2024Article
- Parameterisation and Prediction of Intra-canal Cochlear Structures.Annals of biomedical engineering · 2024Article
- Synchrotron Phase-Contrast Imaging and Cochlear Otosclerosis: A Case Report.Audiology & neuro-otology · 2024Article
- High-Resolution Phase-Contrast Tomography on Human Collagenous Tissues: A Comprehensive Review.Tomography (Ann Arbor, Mich.) · 2023Review
- Imaging of excised cochleae by micro-CT: staining, liquid embedding, and image modalities.Journal of medical imaging (Bellingham, Wash.) · 2023Article
- Quantitative Evaluation of the 3D Anatomy of the Human Osseous Spiral Lamina Using MicroCT.Journal of the Association for Research in Otolaryngology : JARO · 2023Article
- Mortui vivos docent: a modern revival of temporal bone plug harvests.Frontiers in neuroscience · 2023Article
- Reversible contrast enhancement for visualization of human temporal bones using micro computed tomography.Frontiers in surgery · 2022Article
- Otosclerosis under microCT: New insights into the disease and its anatomy.Frontiers in radiology · 2022Article
- Three-Dimensional High-Resolution Temporal Bone Histopathology Identifies Areas of Vascular Vulnerability in the Inner Ear.Audiology & neuro-otology · 2022Article
- The Panoramic ECAP Method: Estimating Patient-Specific Patterns of Current Spread and Neural Health in Cochlear Implant Users.Journal of the Association for Research in Otolaryngology : JARO · 2021Review
- Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter.Scientific reports · 2021Article
- Light sheet microscopy of the gerbil cochlea.The Journal of comparative neurology · 2021Article
Corrections and comments
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Authors and funding
6 authors at 4 institutions in 2 countries.
Funding
Abstract
The gold standard method for visualizing the pathologies underlying human sensorineural hearing loss has remained post-mortem histology for over 125 years, despite awareness that histological preparation induces severe artifacts in biological tissue. Historically, the transition from post-mortem assessment to non-invasive clinical biomedical imaging in living humans has revolutionized diagnosis and treatment of disease; however, innovation in non-invasive techniques for cellular-level intracochlear imaging in humans has been difficult due to the cochlea's small size, complex 3D configuration, fragility, and deep encasement within bone. Here we investigate the ability of synchrotron radiation-facilitated X-ray absorption and phase contrast imaging to enable visualization of sensory cells and nerve fibers in the cochlea's sensory epithelium
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.