ArticleBiomedical optics express2018
Novel analysis of fNIRS acquired dynamic hemoglobin concentrations: application in young children with autism spectrum disorder.
Article in Biomedical optics express, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
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Who cites it
6 citing papers in PubMed, 1 synthesis or guideline pooled it, 10 citations in OpenAlex.
- Cortical Region Reporting Patterns in Neurodevelopmental Disorders: A Systematic Review of fNIRS Studies.Biosensors · 2026Pooled it
- Linking Connectivity Dynamics to Symptom Severity and Cognitive Abilities in Children with Autism Spectrum Disorder: An FNIRS Study.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2025Article
- A Potential Biomarker of Brain Activity in Autism Spectrum Disorders: A Pilot fNIRS Study in Female Preschoolers.Brain sciences · 2023Article
- Looking for "fNIRS Signature" in Autism Spectrum: A Systematic Review Starting From Preschoolers.Frontiers in neuroscience · 2022Review
- Frontal Functional Network Disruption Associated with Amyotrophic Lateral Sclerosis: An fNIRS-Based Minimum Spanning Tree Analysis.Frontiers in neuroscience · 2020Article
- Power spectrum of spontaneous cerebral homodynamic oscillation shows a distinct pattern in autism spectrum disorder.Biomedical optics express · 2019Article
Corrections and comments
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Authors and funding
3 authors at 2 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
A novel analysis of the spatial complexity of functional connectivity (SCFC) was proposed to investigate the spatial complexity of multiple dynamic functional connectivity series in an fNIRS study, using an approach combining principal component analysis and normalized entropy. The analysis was designed to describe the complex spatial features of phase synchrony based dynamic functional connectivity (dFC), which are unexplained in traditional approaches. The feasibility and validity of this method were verified in a sample of young patients with autism spectrum disorders (ASD). Our results showed that there were information exchange deficits in the right prefrontal cortex (PFC) of children with ASD, with markedly higher interregion SCFCs between the right PFC and other brain regions than those of normal controls. Furthermore, the global SCFC was significantly higher in young patients with ASD, along with considerably higher intraregion SCFCs in the prefrontal and temporal lobes which represents more diverse information exchange in these areas. The study suggests a novel method to analyze the fNIRS required dynamic hemoglobin concentrations by using concepts of SCFC. Moreover, the clinical results extend our understanding of ASD pathology, suggesting the crucial role of the right PFC during the information exchange process.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.