Evidence map›Paper›PMID 30338112›Full record

ArticleObesity science & practice2018

Body mass index and health-related quality of life.

R Apple, L R Samuels, C Fonnesbeck, D Schlundt, S Mulvaney, M Hargreaves, D Crenshaw, K A Wallston, W J Heerman

Abstract read
In one paragraph

Article in Obesity science & practice, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 32 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
32citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

32 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Trial
  3. Trends in cardiometabolic disease and health-related quality of life in the United States, 2001-2022.Quality of life research : an international journal of quality of life aspects of treatment, care and rehabilitation · 2026
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  8. Investigating the Impact of Night Eating Disorder Upon Quality of Life Among University College Students, India.Indian journal of community medicine : official publication of Indian Association of Preventive & Social Medicine · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

R AppleDepartment of Internal Medicine and Pediatrics Vanderbilt University Medical Center Nashville TN USA.ORCID 0000-0001-5645-3584
L R SamuelsDepartment of Biostatistics Vanderbilt University Medical Center Nashville TN USA.
C FonnesbeckDepartment of Biostatistics Vanderbilt University Medical Center Nashville TN USA.
D SchlundtDepartment of Psychology Vanderbilt University Nashville TN USA.
S MulvaneyDepartment of Pediatrics Vanderbilt University Medical Center Nashville TN USA.
M HargreavesDepartment of Internal Medicine Meharry Medical College Nashville TN USA.
D CrenshawCenter for Health Services Research, Institute for Medicine and Public Health Vanderbilt University Nashville TN USA.
K A WallstonCenter for Health Services Research, Institute for Medicine and Public Health Vanderbilt University Nashville TN USA.
W J HeermanDepartment of Pediatrics Vanderbilt University Medical Center Nashville TN USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveThere are conflicting data regarding the association between body mass index (BMI) and health-related quality of life (HRQoL), especially among certain population subgroups and for mental and physical health domains.

methodsThis study analysed the relationship between BMI and HRQoL (Patient-Reported Outcomes Measurement Information System mental and physical health scales) using ordinary least squares regression. Each model allowed for the possibility of a non-linear relationship between BMI and the outcome, adjusting for age, gender, comorbidities, diet and physical activity.

resultsA total of 10,133 respondents were predominantly female (71.7%), White (84.1%), median age of 52.1 years (interquartile range 37.2-63.3) and median BMI of 27.9 (interquartile range 24.0-33.2). In adjusted models, BMI was significantly associated with physical and mental HRQoL (

conclusionsThis study demonstrates a non-linear association of variable clinical relevance between BMI and HRQoL after adjusting for demographic factors and comorbidities. The relationship between BMI and HRQoL is nuanced and impacted by gender and age. These findings challenge the idea of obesity as a main driver of reduced HRQoL, particularly among women and with respect to mental HRQoL.

Indexed as

Body mass index (BMI)epidemiologypublic healthquality of life

Identifiers

PMID30338112
PMCPMC6180707

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.