Evidence map›Paper›PMID 30337886›Full record

ArticleFrontiers in physiology2018

Human Atrial Arrhythmogenesis and Sinus Bradycardia in

Dominic G Whittaker, Michael A Colman, Haibo Ni, Jules C Hancox, Henggui Zhang

Open access · goldAbstract read
In one paragraph

Article in Frontiers in physiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
2.7field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 32 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Pro-arrhythmic effects of gain-of-function potassium channel mutations in the short QT syndrome.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Review
  5. Article
  6. Article
  7. European Heart Rhythm Association (EHRA)/Heart Rhythm Society (HRS)/Asia Pacific Heart Rhythm Society (APHRS)/Latin American Heart Rhythm Society (LAHRS) Expert Consensus Statement on the state of genetic testing for cardiac diseases.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2022
    Article
  8. Article
  9. Characterizing the arrhythmogenic substrate in personalized models of atrial fibrillation: sensitivity to mesh resolution and pacing protocol in AF models.Europace : European pacing, arrhythmias, and cardiac electrophysiology : journal of the working groups on cardiac pacing, arrhythmias, and cardiac cellular electrophysiology of the European Society of Cardiology · 2021
    Article
  10. Review
  11. Inherited cardiac arrhythmias.Nature reviews. Disease primers · 2020
    Review
  12. Calibration of ionic and cellular cardiac electrophysiology models.Wiley interdisciplinary reviews. Systems biology and medicine · 2020
    Review
  13. Article
  14. Article
  15. Review
  16. Review
  17. Article
  18. Article
  19. Frontiers in physiology · 2018
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 3 countries.

Dominic G WhittakerSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Michael A ColmanSchool of Biomedical Sciences, Faculty of Biological Sciences, University of Leeds, Leeds, United Kingdom.
Haibo NiBiological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Jules C HancoxBiological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
Henggui ZhangBiological Physics Group, School of Physics and Astronomy, The University of Manchester, Manchester, United Kingdom.
University of Manchester · GBUniversity of California, Davis · USUniversity of Leeds · GB

Funding

British Heart Foundation FS/14/5/30533Medical Research Council MR/M014967/1Medical Research Council MR/M014967/2Wellcome Trust
6 · The paper itself

Abstract

Atrial fibrillation (AF) and sinus bradycardia have been reported in patients with short QT syndrome variant 2 (SQT2), which is underlain by gain-of-function mutations in

Indexed as

anti-arrhythmicarrhythmiaatrial fibrillationKCNQ1 mutationsquinidineshort QT syndromesinus bradycardia

Identifiers

PMID30337886
PMCPMC6180159
OpenAlexW2895359775

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.