ArticleFrontiers in behavioral neuroscience2018
Audiovisual Integration Enhances Stimulus Detection Performance in Mice.
Article in Frontiers in behavioral neuroscience, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers.
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Who cites it
18 citing papers in PubMed.
- Hearing technology and the brain: cognitive function in different hearing device users.Frontiers in aging neuroscience · 2026Article
- Diverse and flexible behavioral strategies arise in recurrent neural networks trained on multisensory decision making.PLoS computational biology · 2025Article
- Article
- Locomotion-dependent auditory gating to the parietal cortex guides multisensory decisions.Nature communications · 2025Article
- Direct Piriform-to-Auditory Cortical Projections Shape Auditory-Olfactory Integration.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2024Article
- Direct piriform-to-auditory cortical projections shape auditory-olfactory integration.bioRxiv : the preprint server for biology · 2024Article
- Claustrum neurons projecting to the anterior cingulate restrict engagement during sleep and behavior.Nature communications · 2024Article
- Article
- Triple dissociation of visual, auditory and motor processing in mouse primary visual cortex.Nature neuroscience · 2024Article
- Article
- Sound Improves Neuronal Encoding of Visual Stimuli in Mouse Primary Visual Cortex.The Journal of neuroscience : the official journal of the Society for Neuroscience · 2023Article
- A novel task to investigate vibrotactile detection in mice.PloS one · 2023Article
- Integration of sensory evidence and reward expectation in mouse perceptual decision-making task with various sensory uncertainties.iScience · 2021Article
- Auditory input enhances somatosensory encoding and tactile goal-directed behavior.Nature communications · 2021Article
- Approaches to Understanding Multisensory Dysfunction in Autism Spectrum Disorder.Autism research : official journal of the International Society for Autism Research · 2020Review
- Cross-Talk of Low-Level Sensory and High-Level Cognitive Processing: Development, Mechanisms, and Relevance for Cross-Modal Abilities of the Brain.Frontiers in neurorobotics · 2020Review
- The Visual Cortex in Context.Annual review of vision science · 2019Review
- Indicators and Criteria of Consciousness in Animals and Intelligent Machines: An Inside-Out Approach.Frontiers in systems neuroscience · 2019Article
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5 authors.
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Abstract
The detection of objects in the external world improves when humans and animals integrate object features of multiple sensory modalities. Behavioral and neuronal mechanisms underlying multisensory stimulus detection are poorly understood, mainly because they have not been investigated with suitable behavioral paradigms. Such behavioral paradigms should (i) elicit a robust multisensory gain, (ii) incorporate systematic calibration of stimulus amplitude to the sensory capacities of the individual subject, (iii) yield a high trial count, and (iv) be easily compatible with a large variety of neurophysiological recording techniques. We developed an audiovisual stimulus detection task for head-fixed mice which meets all of these critical behavioral constraints. Behavioral data obtained with this task indicated a robust increase in detection performance of multisensory stimuli compared with unisensory cues, which was maximal when both stimulus constituents were presented at threshold intensity. The multisensory behavioral effect was associated with a change in the perceptual performance which consisted of two components. First, the visual and auditory perceptual systems increased their sensitivity meaning that low intensity stimuli were more often detected. Second, enhanced acuity enabled the systems to better classify whether there was a stimulus or not. Fitting our data to signal detection models revealed that the multisensory gain was more likely to be achieved by integration of sensory signals rather than by stimulus redundancy or competition. This validated behavioral paradigm can be exploited to reliably investigate the neuronal correlates of multisensory stimulus detection at the level of single neurons, microcircuits, and larger perceptual systems.
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