Evidence map›Paper›PMID 30337835›Full record

ArticleMicroporous and mesoporous materials : the official journal of the International Zeolite Association2018

Using double pulsed-field gradient MRI to study tissue microstructure in traumatic brain injury (TBI).

Michal E Komlosh, Dan Benjamini, Elizabeth B Hutchinson, Sarah King, Margalit Haber, Alexandru V Avram, Lynne A Holtzclaw, Abhishek Desai, Carlo Pierpaoli, Peter J Basser

Abstract read
In one paragraph

Article in Microporous and mesoporous materials : the official journal of the International Zeolite Association, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed.

  1. Article
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  5. bioRxiv : the preprint server for biology · 2023
    Article
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  7. Article
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  9. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Michal E KomloshSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Dan BenjaminiSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Elizabeth B HutchinsonSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Sarah KingSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Margalit HaberDepartment of Neurology, University of Pennsylvania, Philadelphia, PA, USA.
Alexandru V AvramSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Lynne A HoltzclawMicroscopy and Imaging Core, NICHD, National Institutes of Health, Bethesda, MD, USA.
Abhishek DesaiLaboratory of Molecular Signaling, NIAAA, National Institutes of Health, Rockville, MD, USA.
Carlo PierpaoliSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.
Peter J BasserSection on Quantitative Imaging and Tissue Sciences, NICHD, National Institutes of Health, Bethesda, MD, USA.

Funding

Imaging Water Diffusion in the Brain and in Other Soft TissuesZIAHD000266 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BASSER, PETER J. · 2009 to 2017
$3.3M
Quantitative Imaging in experimental models of traumatic brain injuryZIAEB000089 · NIBIB · NATIONAL INSTITUTE OF BIOMEDICAL IMAGING AND BIOENGINEERING · PI PIERPAOLI, CARLO · 2017 to 2020
$1.7M
Magnetic Resonance Diffusion Tensor Imaging (DT-MRI) of the BrainZ01HD000266 · NICHD · EUNICE KENNEDY SHRIVER NATIONAL INSTITUTE OF CHILD HEALTH & HUMAN DEVELOPMENT · PI BASSER, PETER J. · 1998 to 2008
$512k
Intramural NIH HHS Z01 HD000266Intramural NIH HHS Z99 HD999999
6 · The paper itself

Abstract

Double pulsed-field gradient (dPFG) MRI is proposed as a new sensitive tool to detect and characterize tissue microstructure following diffuse axonal injury. In this study dPFG MRI was used to estimate apparent mean axon diameter in a diffuse axonal injury animal model and in healthy fixed mouse brain. Histological analysis was used to verify the presence of the injury detected by MRI.

Indexed as

anisotropic diffusionCHIMERADAIDDEdiffusiond-PFGDTImicrostructureMRITBI

Identifiers

PMID30337835
PMCPMC6188654

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.