ArticleJournal of exposure science & environmental epidemiology2019
Assessing the contributions of metals in environmental media to exposure biomarkers in a region of ferroalloy industry.
Article in Journal of exposure science & environmental epidemiology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 37 papers.
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Who cites it
37 citing papers in PubMed.
- Multi-matrix copper exposure is associated with reduced olfactory bulb volume and odor sensitivity in adolescents.medRxiv : the preprint server for health sciences · 2026Article
- Exploring saliva as a biofluid for biomonitoring of diet-related contaminants exposure: insights from a literature mining approach.Journal of exposure science & environmental epidemiology · 2026Review
- Pathophysiology and histological anomalies in testicular tissues of Calosoma olivieri exposed to heavy metals generated by pesticide industries.Scientific reports · 2026Article
- Article
- Metals and metalloids concentrations in adults aged 50 and older from Mexico.Research square · 2025Article
- Internal Cumulated Dose of Toxic Metal(loid)s in a Population Residing near Naturally Occurring Radioactive Material Waste Stacks and an Industrial Heavily Polluted Area with High Mortality Rates in Spain.Journal of xenobiotics · 2025Article
- Sex-specific associations of a ferroalloy metal mixture with motor function in Italian adolescents.Environmental epidemiology (Philadelphia, Pa.) · 2024Article
- Sex-specific associations between co-exposure to multiple metals and externalizing symptoms in adolescence and young adulthood.Environmental research · 2024Article
- An Industry-Relevant Metal Mixture, Iron Status, and Reported Attention-Related Behaviors in Italian Adolescents.Environmental health perspectives · 2024Article
- Assessing the mediating role of iron status on associations between an industry-relevant metal mixture and verbal learning and memory in Italian adolescents.The Science of the total environment · 2024Article
- Early life manganese exposure and reported attention-related behaviors in Italian adolescents.Environmental epidemiology (Philadelphia, Pa.) · 2023Article
- Environmental tobacco smoke exposure is associated with increased levels of metals in children's saliva.Journal of exposure science & environmental epidemiology · 2023Article
- Manganese-Induced Parkinsonism: Evidence from Epidemiological and Experimental Studies.Biomolecules · 2023Review
- Salivary Metabolomic Signatures and Body Mass Index in Italian Adolescents: A Pilot Study.Journal of the Endocrine Society · 2023Article
- Associations of an industry-relevant metal mixture with verbal learning and memory in Italian adolescents: The modifying role of iron status.Environmental research · 2023Article
- Comparative susceptibility of children and adults to neurological effects of inhaled manganese: A review of the published literature.Environmental research · 2023Review
- Topological network properties of resting-state functional connectivity patterns are associated with metal mixture exposure in adolescents.Frontiers in neuroscience · 2023Article
- Animal Models of Childhood Exposure to Lead or Manganese: Evidence for Impaired Attention, Impulse Control, and Affect Regulation and Assessment of Potential Therapies.Neurotherapeutics : the journal of the American Society for Experimental NeuroTherapeutics · 2023Review
- Neuro-environmental interactions: a time sensitive matter.Frontiers in computational neuroscience · 2023Article
- Short- and long-term exposure to trace metal(loid)s from the production of ferromanganese alloys by personal sampling and biomarkers.Environmental geochemistry and health · 2022Article
Corrections and comments
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Authors and funding
12 authors.
Funding
Abstract
Residential proximity to ferroalloy production has been associated with increased manganese exposure, which can adversely affect health, particularly among children. Little is known, however, about which environmental samples contribute most to internal levels of manganese and other ferroalloy metals. We aimed to characterize sources of exposure to metals and evaluate the ability of internal biomarkers to reflect exposures from environmental media. In 717 Italian adolescents residing near ferromanganese industry, we examined associations between manganese, lead, chromium, and copper in environmental samples (airborne particles, surface soil, indoor/outdoor house dust) and biological samples (blood, hair, nails, saliva, urine). In multivariable regression analyses adjusted for child age and sex, a 10% increase in soil Mn was associated with increases of 3.0% (95% CI: 1.1%, 4.9%) in nail Mn and 1.6% (95% CI: -0.2%, 3.4%) in saliva Mn. Weighted-quantile-sum (WQS) regression estimated that higher soil and outdoor dust Mn accounted for most of the effect on nail Mn (WQS weights: 0.61 and 0.22, respectively, out of a total of 1.0). Higher air and soil Mn accounted for most of the effect on saliva Mn (WQS weights: 0.65 and 0.29, respectively). These findings can help inform biomarker selection in future epidemiologic studies and guide intervention strategies in exposed populations.
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