ArticleScientific reports2018
A Microfluidic Device for Simultaneous Extraction of Plasma, Red Blood Cells, and On-Chip White Blood Cell Trapping.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 29 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
29 citing papers in PubMed, 88 citations in OpenAlex.
- Machine Learning-Assisted Rapid Optical Imaging for Label-Free CAR T-Cell Detection in Whole Blood.Biosensors · 2026Article
- Microfluidics-based cell recognition through optimizing suspended cell staining techniques and artificial intelligence.Journal of biological engineering · 2026Article
- Handheld Lab-on-a-Chip System for Label-Free Dual-Plex Detection of Biomarkers Through On-Chip Plasma Separation.Biosensors · 2025Article
- High-efficient white blood cell separation from whole blood using cascaded inertial microfluidics.Talanta · 2025Article
- Ultra-low extracorporeal volume microfluidic leukapheresis is safe and effective in a rat model.Nature communications · 2025Article
- Intelligent Microfluidics for Plasma Separation: Integrating Computational Fluid Dynamics and Machine Learning for Optimized Microchannel Design.Biosensors · 2025Article
- Enhanced cancer cell sorting using lab-on-a-disk pattern design with magnetic and centrifugal forces.Frontiers in bioengineering and biotechnology · 2025Article
- EchoTilt: An Acoustofluidic Method for the Capture and Enrichment of Nanoplastics Directed Toward Drinking Water Monitoring.Micromachines · 2024Article
- Recent developments in microfluidic passive separation to enable purification of platelets for transfusion.Biomicrofluidics · 2024Review
- Capillary Force-Driven Quantitative Plasma Separation Method for Application of Whole Blood Detection Microfluidic Chip.Micromachines · 2024Article
- Recent advances in microfluidic cell separation to enable centrifugation-free, low extracorporeal volume leukapheresis in pediatric patients.Blood transfusion = Trasfusione del sangue · 2023Review
- Numerical Simulation of a Lab-on-Chip for Dielectrophoretic Separation of Circulating Tumor Cells.Micromachines · 2023Article
- Electrochemical point-of-care devices for the diagnosis of sepsis.Current opinion in electrochemistry · 2023Article
- White Blood Cells Classification Using Entropy-Controlled Deep Features Optimization.Diagnostics (Basel, Switzerland) · 2023Article
- Advances in Microfluidics for Single Red Blood Cell Analysis.Biosensors · 2023Review
- Universal pre-mixing dry-film stickers capable of retrofitting existing microfluidics.Biomicrofluidics · 2023Article
- Comparison of Functional Properties of Blood Plasma Collected from Black Goat and Hanwoo Cattle.Food science of animal resources · 2023Article
- Article
- High-Resolution 3D Printing Fabrication of a Microfluidic Platform for Blood Plasma Separation.Polymers · 2022Article
- Multi-Method Diagnosis of Blood Microscopic Sample for Early Detection of Acute Lymphoblastic Leukemia Based on Deep Learning and Hybrid Techniques.Sensors (Basel, Switzerland) · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
This study reports a microfluidic device for whole blood processing. The device uses the bifurcation law, cross-flow method, and hydrodynamic flow for simultaneous extraction of plasma, red blood cells, and on-chip white blood cell trapping. The results demonstrate successful plasma and red blood cell collection with a minimum dilution factor (0.76x) and low haemolysis effect. The extracted red blood cells can also be applied for blood type tests. Moreover, the device can trap up to ~1,800 white blood cells in 20 minutes. The three components can be collected simultaneously using only 6 μL of whole blood without any sample preparation processes. Based on these features, the microfluidic device enables low-cost, rapid, and efficient whole blood processing functionality that could potentially be applied for blood analysis in resource-limited environments or point-of-care settings.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.