Trial reportScientific reports2018
Early childhood exposure to secondhand smoke and behavioural problems in preschoolers.
Trial report in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 36 citations in OpenAlex.
- Association between postnatal environmental tobacco smoke exposure controlling for prenatal exposure and conduct problems in children: A systematic review.Neurotoxicology · 2023Pooled it
- Protocol for a Cluster Randomized Controlled Trial to Reduce Susceptibility to Tobacco Use Among School Going Adolescents in a South-Indian District-(Project TEACH).Indian journal of psychological medicine · 2025Article
- Secondhand smoke exposure and behavioral problems in Japanese schoolchildren.Frontiers in public health · 2025Article
- Article
- The next 1000 days: building on early investments for the health and development of young children.Lancet (London, England) · 2024Review
- Tobacco Smoke Exposure in Children and Adolescents: Prevalence, Risk Factors and Co-Morbid Neuropsychiatric Conditions in a US Nationwide Study.Healthcare (Basel, Switzerland) · 2024Article
- Maternal oxidative stress during pregnancy associated with emotional and behavioural problems in early childhood: implications for foetal programming.Molecular psychiatry · 2023Article
- Early life stress, prenatal secondhand smoke exposure, and the development of internalizing symptoms across childhood.Environmental health : a global access science source · 2023Article
- Public Health Burden of Secondhand Smoking: Case Reports of Lung Cancer and a Literature Review.International journal of environmental research and public health · 2022Review
- The Impact of Air Pollution on Gut Microbiota and Children's Health: An Expert Consensus.Children (Basel, Switzerland) · 2022Review
- Shortened Infant Telomere Length Is Associated with Attention Deficit/Hyperactivity Disorder Symptoms in Children at Age Two Years: A Birth Cohort Study.International journal of molecular sciences · 2022Article
- Cigarette Use among Parents with Children in the Home: A Comparison of Civilian Parents and Parents with a Military Connection.Environmental health insights · 2022Article
- Association of Prenatal, Early Postnatal, or Current Exposure to Secondhand Smoke With Attention-Deficit/Hyperactivity Disorder Symptoms in Children.JAMA network open · 2021Article
- Exposure to Tobacco Smoke and Temperament among U.S. Children 0-5 Years Old.Journal of pediatric psychology · 2021Article
- Associations of household environmental tobacco smoke exposure with respiratory symptoms and utilisation of medical services in healthy young children in Hong Kong.Tobacco induced diseases · 2020Article
- Impact of Nicotine Replacement and Electronic Nicotine Delivery Systems on Fetal Brain Development.International journal of environmental research and public health · 2019Review
- Association of water fluoride and urinary fluoride concentrations with attention deficit hyperactivity disorder in Canadian youth.Environment international · 2019Article
- Prevalence of Mental Health and Neurodevelopmental Conditions in U.S. Children with Tobacco Smoke Exposure.Journal of pediatric health care : official publication of National Association of Pediatric Nurse Associates & PractitionersArticle
- Associations between prenatal and postnatal substance exposure and salivary C-reactive protein in early childhood.Neurotoxicology and teratologyArticle
- Environmental Tobacco Smoke and Educational Self-Regulation and Achievement in First Grade High School Students.Journal of medicine and lifeArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors at 2 institutions in 3 countries.
Funding
Abstract
Evidence on behavioural abnormalities in children exposed to secondhand smoke is limited. This study examined the relation between infant/ toddler cotinine concentration, a biomarker of secondhand smoke exposure, and behavioural problems in preschoolers who were unexposed to maternal smoking during gestation. A prospective cohort of 301 non-smoking mothers with their young children aged ≤18 months visiting postnatal primary care clinics in Hong Kong was enrolled in 2012 and followed by telephone survey 3 years afterwards. Saliva was collected at baseline for cotinine assay. Child behavioural health at 3-year follow-up was assessed by the parent-reported Strengths and Difficulties Questionnaire (SDQ). We conducted multivariable linear regressions to compute regression coefficients (b) of SDQ scores in relation to salivary cotinine level. Mean ± SD age of children at follow-up was 3.7 ± 0.5 years and 50.8% were boys. After adjusting for age, sex, birthweight, household income, housing type, maternal education and depressive symptoms, greater cotinine concentrations during early childhood were associated with greater conduct problems (b = 0.90, 95% CI 0.03-1.76) and hyperactivity/ inattention (b = 1.12, 95% CI 0.07-2.17) at preschool age. This study corroborates previous findings on the potential role of secondhand smoke in development of child behavioural problems.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.