ArticleScientific reports2018
Neutralizing antibodies to Severe Fever with Thrombocytopenia Syndrome Virus in general population, Shandong Province, China.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.
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Who cites it
7 citing papers in PubMed, 12 citations in OpenAlex.
- Serological and molecular assessment of severe fever with thrombocytopenia syndrome virus infection in wild boars from two adjacent endemic prefectures in Japan.The Journal of veterinary medical science · 2026Article
- Epidemiological Characteristics of Severe Fever with Thrombocytopenia Syndrome.The American journal of tropical medicine and hygiene · 2025Review
- Seroprevalence of severe fever with thrombocytopenia syndrome using specimens from the Korea National Health & Nutrition Examination Survey.PLoS neglected tropical diseases · 2023Article
- Infection with severe fever with thrombocytopenia virus in healthy population: a cohort study in a high endemic region, China.Infectious diseases of poverty · 2021Article
- Severe fever with thrombocytopenia syndrome with re-infection in China: a case report.Infectious diseases of poverty · 2021Article
- Immune Modulation and Immune-Mediated Pathogenesis of Emerging Tickborne Banyangviruses.Vaccines · 2019Review
- Evolving therapeutic strategies for severe fever with thrombocytopenia syndrome: from past to future.Therapeutic advances in infectious diseaseReview
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Authors and funding
4 authors at 3 institutions in 1 country.
Funding
Abstract
Severe fever with thrombocytopenia syndrome (SFTS) is an emerging infectious disease caused by SFTS virus (SFTSV) in East Asia. The research on seroprevalence of SFTSV in healthy people and risk factors had been detailed. However, the levels of neutralizing antibodies against SFTSV in general population were currently unclear. In the present study, we tested 1375 healthy persons from Penglai County, eastern China, for SFTSV neutralizing antibodies; 0.58% (8/1,375) was positive and the positive rates were not significantly different among people at different age groups, occupations and genders. Besides, a follow-up study was conducted and the titer of neutralizing antibodies decreased over time in all eight people but one, and the neutralizing antibodies of five lasted for the entire study period of seven years. Our results suggesting that subclinical infection or a relatively mild form of SFTS illness is occurring in this population, but a small percentage of sera have neutralizing capacity to SFTSV. Hence, most people are just susceptible to SFTSV infection.
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