ArticleScientific reports2018
Dissociation between the processing of humorous and monetary rewards in the 'motivation' and 'hedonic' brains.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.
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Who cites it
12 citing papers in PubMed, 27 citations in OpenAlex.
- A qualitative study investigating the role of humor in supporting recovery from addiction.Journal of substance use and addiction treatment · 2026Article
- Optogenetics and chemogenetics: key tools for modulating neural circuits in rodent models of depression.Frontiers in neural circuits · 2025Review
- Personalized neural responses to self and filial reward: Functional and structural responses to motivational cues.AIMS neuroscience · 2025Article
- Comparative basolateral amygdala connectomics reveals dissociable single-neuron projection patterns to frontal cortex in macaques and mice.Current biology : CB · 2024Article
- Appetitive conditioning with pornographic stimuli elicits stronger activation in reward regions than monetary and gaming-related stimuli.Human brain mapping · 2024Article
- The role of pituitary adenylate cyclase-activating polypeptide neurons in the hypothalamic ventromedial nucleus and the cognate PAC1 receptor in the regulation of hedonic feeding.Frontiers in nutrition · 2024Article
- Relevance of the anterior cingulate cortex volume and personality in motivated physical activity behaviors.Communications biology · 2023Article
- Striatal hypoactivation during monetary loss anticipation in individuals with substance use disorders in a heterogenous urban American Indian sample.Drug and alcohol dependence · 2023Article
- Amygdala-frontoparietal effective connectivity in creativity and humor processing.Human brain mapping · 2023Article
- Verification of the Four-Stage Model of Humor Processing: Evidence from an fMRI Study by Three-Element Verbal Jokes.Brain sciences · 2023Article
- Effective connectivity of the amygdala during the consumption of erotic, sexual humor, and monetary rewards with a DCM-PEB approach.PloS one · 2022Article
- Social and Nonsocial Reward Anticipation in Typical Development and Autism Spectrum Disorders: Current Status and Future Directions.Current psychiatry reports · 2021Review
Corrections and comments
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Authors and funding
3 authors at 3 institutions in 1 country.
Funding
Abstract
Humor elicits feelings of amusement and can be thought of as a social reward. We identified distinct mesolimbic reward system (MRS) processing patterns for monetary and humorous rewards. During both the reward anticipation and outcome phases, the nucleus accumbens (NAc) and anterior cingulate cortex (ACC) were active in response to monetary cues and monetary gains, while the amygdala and midbrain showed a differential response to humorous rewards, apparently driven by the hedonic enjoyment and appreciation of humor consumption. Psychophysiological interaction analysis (PPI) further demonstrated the functional coupling of the amygdala-midbrain circuit in response to humorous gains during the reward outcome phase, while neural signaling was observed in the NAc-ACC circuit during both the reward anticipation and outcome phases in response to monetary rewards. This is consistent with a view in which the NAc plays a key role in the 'motivation brain', and the amygdala in the 'hedonic brain'. The findings further suggest that the neural mechanisms underlying reward consumption are more modality-specific than those underlying reward anticipation. Our study contributes to a growing understanding of neural responses to social rewards and represent an important first step toward understanding the neural processing of humor as one significant type of social reward.
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