ArticleNature communications2018
Cell shape-independent FtsZ dynamics in synthetically remodeled bacterial cells.
Article in Nature communications, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed, 29 citations in OpenAlex.
- Uropathogenic Escherichia coli proliferate as a coccoid morphotype inside human host cells.PLoS biology · 2025Article
- Protocol for single-molecule labeling and tracking of bacterial cell division proteins.STAR protocols · 2024Article
- Application of nanotags and nanobodies for live cell single-molecule imaging of the Z-ring in Escherichia coli.Current genetics · 2023Article
- Assembly dynamics of FtsZ and DamX during infection-related filamentation and division in uropathogenic E. coli.Nature communications · 2022Article
- Asymmetric peptidoglycan editing generates cell curvature in Bdellovibrio predatory bacteria.Nature communications · 2022Article
- The Longitudinal Dividing BacteriumInternational journal of molecular sciences · 2022Article
- FtsZ-mediated fission of a cuboid bacterial symbiont.iScience · 2022Article
- FtsZ dynamics in bacterial division: What, how, and why?Current opinion in cell biology · 2021Review
- Treadmilling FtsZ polymers drive the directional movement of sPG-synthesis enzymes via a Brownian ratchet mechanism.Nature communications · 2021Article
- The Stress-Active Cell Division Protein ZapE Alters FtsZ Filament Architecture to Facilitate Division inFrontiers in microbiology · 2021Article
- Bacterial Vivisection: How Fluorescence-Based Imaging Techniques Shed a Light on the Inner Workings of Bacteria.Microbiology and molecular biology reviews : MMBR · 2020Review
- Artificial modulation of cell width significantly affects the division time of Escherichia coli.Scientific reports · 2020Article
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- Geometric Effect for Biological Reactors and Biological Fluids.Bioengineering (Basel, Switzerland) · 2018Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
FtsZ is the main regulator of bacterial cell division. It has been implicated in acting as a scaffolding protein for other division proteins, a force generator during constriction, and more recently, as an active regulator of septal cell wall production. FtsZ assembles into a heterogeneous structure coined the Z-ring due to its resemblance to a ring confined by the midcell geometry. Here, to establish a framework for examining geometrical influences on proper Z-ring assembly and dynamics, we sculpted Escherichia coli cells into unnatural shapes using division- and cell wall-specific inhibitors in a micro-fabrication scheme. This approach allowed us to examine FtsZ behavior in engineered Z-squares and Z-hearts. We use stimulated emission depletion (STED) nanoscopy to show that FtsZ clusters in sculpted cells maintain the same dimensions as their wild-type counterparts. Based on our results, we propose that the underlying membrane geometry is not a deciding factor for FtsZ cluster maintenance and dynamics in vivo.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.