Evidence map›Paper›PMID 30337436›Full record

ArticleAJNR. American journal of neuroradiology2018

Prospective Multicenter Study of Changes in MTT after Aneurysmal SAH and Relationship to Delayed Cerebral Ischemia in Patients with Good- and Poor-Grade Admission Status.

A Murphy, T-Y Lee, T R Marotta, J Spears, R L Macdonald, R I Aviv, A Baker, A Bharatha

Abstract readMulticenter Study
In one paragraph

Article in AJNR. American journal of neuroradiology, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Guideline
  2. Pooled it
  3. Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

A MurphyFrom the Division of Diagnostic and Interventional Neuroradiology (A.M., T.R.M., A. Bharatha).ORCID 0000-0002-1792-8847
T-Y LeeLawson Health Research Institute and Robarts Research Institute (T.-Y.L.), University of Western Ontario, London, Ontario, Canada.ORCID 0000-0001-7605-9752
T R MarottaFrom the Division of Diagnostic and Interventional Neuroradiology (A.M., T.R.M., A. Bharatha).ORCID 0000-0002-2480-2054
J SpearsDivision of Neurosurgery (T.R.M., J.S., A. Bharatha), Department of Surgery, St. Michael's Hospital, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0001-8458-1524
R L MacdonaldLabatt Family Centre of Excellence in Brain Injury and Trauma Research (R.L.M.).ORCID 0000-0003-4024-8070
R I AvivDepartment of Medical Imaging (R.I.A.), Sunnybrook Hospital, Toronto, Ontario, Canada.ORCID 0000-0003-0259-970X
A BakerDepartments of Anesthesia and Critical Care Medicine (A. Baker).ORCID 0000-0002-6312-5172
A BharathaFrom the Division of Diagnostic and Interventional Neuroradiology (A.M., T.R.M., A. Bharatha) BharathaA@smh.ca.ORCID 0000-0002-7923-7865

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposePatients with aneurysmal SAH and good clinical status at admission are considered at a lower risk for delayed cerebral ischemia. Prolonged MTT may be associated with an increased risk. It is unclear whether this is dependent on clinical status. Our purpose was to determine whether increased MTT within 3 days of aneurysmal SAH compared with baseline is associated with a higher risk of delayed cerebral ischemia in patients with good (World Federation of Neurosurgical Societies I-III) versus poor (World Federation of Neurosurgical Societies IV-V) admission status. MATERIALS AND

methodsThis prolonged MTT was a multicenter, prospective cohort investigation of 87 patients with aneurysmal SAH. MTT was measured at admission before aneurysm treatment (MTT1) and following repair (MTT2) within 3 days of admission; MTT

resultsIn patients with a good grade (

conclusionsPatients in good clinical condition following aneurysmal SAH but with increasing MTT in the first few days after aneurysmal SAH are at high risk of delayed cerebral ischemia and warrant close clinical monitoring.

Indexed as

AdultBrain IschemiaCohort StudiesFemaleHumansMaleMiddle AgedNeuroimagingPerfusion ImagingProspective StudiesSubarachnoid HemorrhageTomography, X-Ray Computed

Identifiers

PMID30337436
PMCPMC7655376

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.