Evidence map›Paper›PMID 30337376›Full record

ArticleDevelopment (Cambridge, England)2018

TWE-PRIL reverse signalling suppresses sympathetic axon growth and tissue innervation.

Laura Howard, Erin Wosnitzka, Darian Okakpu, Matthew A White, Sean Wyatt, Alun M Davies

Open access · hybridAbstract read
In one paragraph

Article in Development (Cambridge, England), 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
0.6field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 10 citations in OpenAlex.

  1. Article
  2. Article
  3. How CD40L reverse signaling regulates axon and dendrite growth.Cellular and molecular life sciences : CMLS · 2021
    Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 3 countries.

Laura HowardSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Erin WosnitzkaSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Darian OkakpuSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Matthew A WhiteSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Sean WyattSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK.
Alun M DaviesSchool of Biosciences, Cardiff University, Museum Avenue, Cardiff, CF10 3AT, UK daviesalun@cf.ac.uk.ORCID 0000-0001-7784-9000
Cardiff University · GBKing's College London · GBTechnische Universität Dresden · DE

Funding

Wellcome Trust 103852
6 · The paper itself

Abstract

TWE-PRIL is a naturally occurring fusion protein of components of two TNF superfamily members: the extracellular domain of APRIL; and the intracellular and transmembrane domains of TWEAK with no known function. Here, we show that

Indexed as

Signal TransductionAnimalsAxonsB-Cell Maturation AntigenCells, CulturedCytokine TWEAKEnzyme ActivationExtracellular Signal-Regulated MAP KinasesGene Knockdown TechniquesMiceModels, BiologicalNerve Growth FactorPhenotypeRNA, Small InterferingSolubilitySuperior Cervical GanglionB-Cell Maturation AntigenCytokine TWEAKExtracellular Signal-Regulated MAP KinasesNerve Growth FactorRNA, Small InterferingTnfrsf17 protein, mouseTnfsf12 protein, mouseTnfsf13 protein, mouseTnfsfm13 protein, mouseTumor Necrosis Factor Ligand Superfamily Member 13Reverse signallingSympathetic axonsTissue innervationTNFSF13TNFSFM13TNF superfamily

Identifiers

PMID30337376
PMCPMC6262789
OpenAlexW2897562466

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.