Evidence map›Paper›PMID 30337352›Full record

ArticleThe Journal of cell biology2019

CCP1 promotes mitochondrial fusion and motility to prevent Purkinje cell neuron loss in

Stephen Gilmore-Hall, Jennifer Kuo, Jacqueline M Ward, Rabaab Zahra, Richard S Morrison, Guy Perkins, Albert R La Spada

Open access · bronzeAbstract read
In one paragraph

Article in The Journal of cell biology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
1.7field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 39 citations in OpenAlex.

  1. Article
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  9. Article
  10. NEKL-4 regulates microtubule stability and mitochondrial health inbioRxiv : the preprint server for biology · 2024
    Article
  11. Disruption of axonal transport in neurodegeneration.The Journal of clinical investigation · 2023
    Review
  12. Article
  13. Review
  14. Review
  15. Review
  16. Article
  17. Review
  18. Pathogenic role of delta 2 tubulin in bortezomib-induced peripheral neuropathy.Proceedings of the National Academy of Sciences of the United States of America · 2021
    Article
  19. Article
  20. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Stephen Gilmore-HallDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.ORCID 0000-0001-5919-2033
Jennifer KuoDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
Jacqueline M WardDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
Rabaab ZahraDepartment of Pediatrics, University of California, San Diego, La Jolla, CA.
Richard S MorrisonDepartment of Neurosurgery, University of Washington, Seattle, WA.ORCID 0000-0002-5115-446X
Guy PerkinsNational Center for Microscopy and Imaging Research, University of California, San Diego, La Jolla, CA.ORCID 0000-0002-1878-8735
Albert R La SpadaDepartment of Pediatrics, University of California, San Diego, La Jolla, CA al.laspada@duke.edu.ORCID 0000-0001-6151-2964
University of California San Diego · USDuke University · USUniversity of Washington · US

Funding

IVEM and Image Analysis ResourceP41GM103412 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI ELLISMAN, MARK H · 2012 to 2019
$17.9M
Training Program in Basic Clinical GeneticsT32GM008666 · NIGMS · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HAMILTON, BRUCE A · 1998 to 2021
$8.6M
Molecular genetic regulation of autophagy in health and neurodegenerative diseaseR01AG033082 · NIA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI LA SPADA, ALBERT R · 2009 to 2019
$4.0M
ROLE OF Nna1 IN RETINAL AND CEREBELLAR NEURODEGENERATIONR01EY014997 · NEI · UNIVERSITY OF WASHINGTON · PI LA SPADA, ALBERT R · 2004 to 2013
$2.9M
TRAINING IN NEUROSCIENCE RELATED TO DRUG ABUSET32DA007315 · NIDA · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI HOOK, VIVIAN Y. H · 2000 to 2013
$2.7M
NEI NIH HHS R01 EY014997NIA NIH HHS R01 AG033082NIDA NIH HHS T32 DA007315NIGMS NIH HHS P41 GM103412NIGMS NIH HHS T32 GM008666
6 · The paper itself

Abstract

A perplexing question in neurodegeneration is why different neurons degenerate. The Purkinje cell degeneration (

Indexed as

AnimalsAxonal TransportCytoskeletal ProteinsDisease Models, AnimalDrosophila melanogasterGene Expression RegulationGlutamineGTP-Binding ProteinsMaleMiceMice, KnockoutMitochondriaMitochondrial DynamicsNerve Tissue ProteinsNeurodegenerative DiseasesPhenotypeCcdc115 protein, mouseCytoskeletal ProteinsDRP1 protein, DrosophilaGlutamineGTP-Binding ProteinsNerve Tissue Proteinsparkin proteinTubulinUbiquitin-Protein Ligases

Identifiers

PMID30337352
PMCPMC6314562
OpenAlexW2896267178

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.