Trial reportThe Journal of pediatrics2019
Weaning of Moderately Preterm Infants from the Incubator to the Crib: A Randomized Clinical Trial.
Trial report in The Journal of pediatrics, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. It is linked to 3 registered trials, which are not on this map. Cited by 14 papers, 3 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Incubator Weaning of Moderately Preterm Infants: A Randomized Controlled Trial
Feasibility and Safety of Earlier Weaning of Preterm Newborn From Incubator to Cot at 1400 Grams
Early Weaning of Infants Less Than 1800 Grams From Incubator To Crib
Who cites it
14 citing papers in PubMed, 3 syntheses or guidelines pooled it.
- Eligible Infants Included in Neonatal Clinical Trials and Reasons for Noninclusion: A Systematic Review.JAMA network open · 2024Pooled it
- Race and Ethnicity of Infants Enrolled in Neonatal Clinical Trials: A Systematic Review.JAMA network open · 2023Pooled it
- EFFECTS OF HAMMOCK POSITIONING ON CLINICAL PARAMETERS IN PRETERM INFANTS ADMITTED TO A NEONATAL INTENSIVE CARE UNIT: A SYSTEMATIC REVIEW.Revista paulista de pediatria : orgao oficial da Sociedade de Pediatria de Sao Paulo · 2020Pooled it
- Effects of an early transfer from incubator to a warming crib in very low birthweight preterm infants.BMC pediatrics · 2024Trial
- Reducing the Length of Hospitalization for Premature Infants Using a Quality Improvement Project.Journal of clinical medicine · 2026Article
- Effects of early parenteral nutrition on the development of premature infants born at 22-23 weeks of gestation: a retrospective cohort study evaluated by brain magnetic resonance imaging.European journal of clinical nutrition · 2025Article
- Heart rate variability and amplitude-integrated electroencephalography measured shortly after birth and time to reach clinical milestones: a pilot study in late preterm infants.Frontiers in pediatrics · 2025Article
- Assessment of Skin Maturity by LED Light at Birth and Its Association With Lung Maturity: Clinical Trial Secondary Outcomes.JMIR biomedical engineering · 2023Article
- Developmental care pathway for hospitalised infants with CHD: on behalf of the Cardiac Newborn Neuroprotective Network, a Special Interest Group of the Cardiac Neurodevelopmental Outcome Collaborative.Cardiology in the young · 2023Article
- Contributions of the NICHD neonatal research network's generic database to documenting and advancing the outcomes of extremely preterm infants.Seminars in perinatology · 2022Article
- Overview of the neonatal research network: History, contributions, challenges, and future.Seminars in perinatology · 2022Review
- Body Weight Gain Status during the Incubator Weaning Process in Very Low Birth Weight Premature Infants.Children (Basel, Switzerland) · 2022Article
- Transferring preterm infants into an open cot using a heated mattress at ≤ 1400 g.Journal of perinatology : official journal of the California Perinatal Association · 2019Article
- A Quality Improvement Initiative to Improve Normothermia While Transitioning Premature Infants to an Open Crib.Pediatric quality & safetyArticle
Corrections and comments
- Commented on by
- Commented on by
- Erratum issuedCorrigendum.2020
Authors and funding
29 authors.
Funding
Abstract
objectiveTo assess whether length of hospital stay is decreased among moderately preterm infants weaned from incubator to crib at a lower vs higher weight. STUDY
designThis trial was conducted in the Eunice Kennedy Shriver National Institute of Child Health and Human Development Neonatal Research Network. Infants with gestational ages 29-33 weeks, birthweight <1600 g, and in an incubator were randomly assigned to a weaning weight of 1600 or 1800 g. Within 60 to 100 g of weaning weight, the incubator temperature was decreased by 1.0°C to 1.5°C every 24 hours until 28.0°C. The infants were weaned to the crib following stable temperature at 36.5°C to 37.4°C for 8 to 12 hours. Clothing and bedcoverings were standardized. The primary outcome was length of hospital stay from birth to discharge; secondary outcomes included length of stay and growth velocity from weaning to discharge. Adverse events were monitored.
resultsOf 1565 infants screened, 885 were eligible, and 366 enrolled-187 to the 1600-g and 179 to the 1800-g group. Maternal and neonatal characteristics did not differ among weight groups. Length of hospital stay was a median of 43 days in the lower and 41 days in the higher weight group (P = .12). Growth velocity from completion of weaning to discharge was higher in the lower weight group, 13.7 g/kg/day vs 12.8 g/kg/day (P = .005). Groups did not differ in adverse events.
conclusionsAmong moderately preterm neonates, weaning from incubator to crib at a lower weight did not decrease length of stay, but was safe and was accompanied by higher weight gain after weaning.
trial registrationClinicalTrials.gov: NCT02160002.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.