Evidence map›Paper›PMID 30336747›Full record

ArticleInternational journal of STD & AIDS2019

Prevalence and determinants of anal human papillomavirus infection in men who have sex with men and transgender women.

Ross D Cranston, Alex Carballo-Diéguez, Holly Gundacker, Barbra A Richardson, Rebecca Giguere, Curtis Dolezal, Aaron Siegel, Ratiya P KunjaraNaAyudhya, Kailazarid Gomez, Jeanna M Piper and 3 more

2 registry-linked trialsOpen access · greenAbstract read
In one paragraph

Article in International journal of STD & AIDS, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT01687218 phase2completednot on this map

A Phase 2 Randomized Sequence Open Label Expanded Safety and Acceptability Study of Oral Emtricitabine/Tenofovir Disoproxil Fumarate Tablet and Rectally-Applied Tenofovir Reduced-Glycerin 1% Gel

TypeinterventionalSponsorCONRADRan2013 to 2015Enrolled195ConditionsHIVArmsOral FTC/TDF (Daily Emtricitabine/Tenofovir Disoproxil fumarate Tablet), Rectal Daily TFV RG 1% gel (Rectally applied Tenofovir Reduced Glycerin 1% Gel), Rectal RAI-associated TFV RG 1% gel (Receptive Anal Intercourse Associated rectally applied Tenofovir Reduced Glycerin 1% Gel)
NCT06920589 nacompletednot on this mapstarted 2021, after this paper: background citation

Intervention Toward Knowledge of Human Papillomavirus in Homosexual Males

TypeinterventionalSponsorHospital Univeristario Benemerita Universidad Autonoma de PueblaRan2021 to 2022Enrolled40ConditionsHuman Papilloma Virus (HPV)ArmsSafe and Protected Sex" intervention targeting HPV, Diptych of the Secretary of Health in Mexico
3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 28 citations in OpenAlex.

  1. Trial
  2. Article
  3. Article
  4. Article
  5. Article
  6. Article
  7. Article
  8. Increased CD4BMC infectious diseases · 2022
    Article
  9. Article
  10. How Much Does HIV Positivity Affect the Presence of Oral HPV? A Molecular Epidemiology Survey.International journal of environmental research and public health · 2021
    Article
  11. Article
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 8 institutions in 2 countries.

Ross D Cranston1 Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.ORCID 0000-0002-2687-6217
Alex Carballo-Diéguez2 New York State Psychiatry Institute and Columbia University, New York, NY, USA.
Holly Gundacker3 Fred Hutchinson Cancer Research Center - Statistical Center for HIV/AIDS Research and Prevention, Seattle, WA, USA.
Barbra A Richardson3 Fred Hutchinson Cancer Research Center - Statistical Center for HIV/AIDS Research and Prevention, Seattle, WA, USA.
Rebecca Giguere2 New York State Psychiatry Institute and Columbia University, New York, NY, USA.
Curtis Dolezal2 New York State Psychiatry Institute and Columbia University, New York, NY, USA.
Aaron Siegel5 Magee-Womens Research Institute, Pittsburgh, PA, USA.
Ratiya P KunjaraNaAyudhya5 Magee-Womens Research Institute, Pittsburgh, PA, USA.
Kailazarid Gomez6 FHI 360, Durham, NC, USA.
Jeanna M Piper7 National Institute of Allergy and Infectious Disease, Bethesda, MD, USA.
Javier R Lama8 Asociación Civil Impacta Salud y Educación, Lima, Peru.
Ian McGowan1 Department of Medicine, University of Pittsburgh, Pittsburgh, PA, USA.
MTN-017 Protocol Team
New York Psychoanalytic Society and Institute · USMagee-Womens Research Institute · USUniversity of Pittsburgh · USAsociación Civil Impacta Salud y Educación · PEFamily Health International 360 · USFred Hutch Cancer Center · USNational Institute of Allergy and Infectious Diseases · USUniversity of Washington · US

Funding

Microbicide Trials NetworkUM1AI068633 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI HILLIER, SHARON L. · 2011 to 2021
$175.0M
Statistical and Data Management Center (SDMC): Microbicide Trials NetworkUM1AI068615 · NIAID · FRED HUTCHINSON CANCER RESEARCH CENTER · PI BROWN, ELIZABETH RENATA · 2011 to 2021
$66.5M
Laboratory Center (LC): Microbicide Trials NetworkUM1AI106707 · NIAID · MAGEE-WOMEN'S RES INST AND FOUNDATION · PI MELLORS, JOHN W, ROHAN, LISA CENCIA · 2014 to 2021
$27.1M
NIAID NIH HHS UM1 AI068615NIAID NIH HHS UM1 AI068633NIAID NIH HHS UM1 AI106707
6 · The paper itself

Abstract

Human papillomavirus (HPV) prevalence varies by population. This study investigated anal HPV type detection risk by country in a population of men who have sex with men (MSM) and transgender women (TW) at risk of HIV. Sexually active HIV-1-uninfected MSM and TW were enrolled at eight sites: four in the United States (US), two in Thailand, one in Peru, and one in South Africa. Baseline anal HPV swabs were collected, and DNA typing was performed. One hundred and ninety-five participants, 76 (42%) from the US, had a mean age of 30.9 years (range 18-64). In 182 participants with results available, anal HPV infection was common with 169 (93%) with ≥1 type, 132 (73%) with ≥1 nine-valent vaccine types, and 66 (36%) with HPV 16. Participants in the US had a higher prevalence of HPV 16 (56%, p = 0.004) and HPV 6 (69%, p < 0.001) compared to the other regions. Stimulant drug use was significantly associated with HPV 6 detection. Anal HPV is highly prevalent in this population of MSM and TW sampled from four countries, with HPV 16 the most commonly detected type. The nine-valent HPV vaccine has the potential to provide significant protection if given prior to exposure.

Indexed as

AdolescentAdultAgedAnal CanalFemaleHomosexuality, MaleHuman papillomavirus 16Human papillomavirus 6HumansMaleMiddle AgedPapillomaviridaePapillomavirus InfectionsPeruPolymerase Chain ReactionPrevalenceanalHuman papillomavirusmen who have sex with menmicrobicidetransgender women

Identifiers

PMID30336747
PMCPMC6552657
OpenAlexW2897778286

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.