Evidence map›Paper›PMID 30336677›Full record

ArticleOrganic letters2018

Synthesis of Phthalans Via Copper-Catalyzed Enantioselective Cyclization/Carboetherification of 2-Vinylbenzyl Alcohols.

Dake Chen, Sherry R Chemler

Abstract read
In one paragraph

Article in Organic letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Review
  2. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors.

Dake ChenDepartment of Chemistry , State University of New York at Buffalo , Buffalo , New York 14260 , United States.
Sherry R ChemlerDepartment of Chemistry , State University of New York at Buffalo , Buffalo , New York 14260 , United States.ORCID 0000-0001-6702-5032

Funding

New Methods for Nitrogen Heterocycle SynthesisR01GM078383 · NIGMS · STATE UNIVERSITY OF NEW YORK AT BUFFALO · PI CHEMLER, SHERRY R · 2006 to 2023
$5.6M
NIGMS NIH HHS R01 GM078383
6 · The paper itself

Abstract

Enantiomerically enriched phthalans were synthesized efficiently via an enantioselective copper-catalyzed alkene carboetherification reaction. In this reaction, 2-vinylbenzyl alcohols enantioselectively cyclize then couple with vinylarenes. The utility of the method was demonstrated by the enantioselective synthesis of ( R)-fluspidine, a σ

Indexed as

AlkenesBenzofuransBenzyl AlcoholsCatalysisCopperCyclizationStereoisomerismVinyl CompoundsAlkenesBenzofuransBenzyl AlcoholsCopperphthalanphthalideVinyl Compounds

Identifiers

PMID30336677
PMCPMC6459690

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.