Evidence map›Paper›PMID 30336549›Full record

ArticleInternational journal of molecular sciences2018

Preparation and Characterization of Functionalized Graphene Oxide Carrier for siRNA Delivery.

Jing Li, Xu Ge, Chunying Cui, Yifan Zhang, Yifan Wang, Xiaoli Wang, Qi Sun

Open access · goldAbstract read
In one paragraph

Article in International journal of molecular sciences, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
1.4field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 34 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. siRNA and targeted delivery systems in breast cancer therapy.Clinical & translational oncology : official publication of the Federation of Spanish Oncology Societies and of the National Cancer Institute of Mexico · 2023
    Review
  5. Research Status and Prospect of Non-Viral Vectors Based on siRNA: A Review.International journal of molecular sciences · 2023
    Review
  6. Review
  7. Review
  8. Review
  9. Article
  10. Article
  11. Article
  12. Article
  13. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 1 institution in 1 country.

Jing LiDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. lijingcr7@foxmail.com.
Xu GeDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. gexu1991@foxmail.com.
Chunying CuiDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. ccy@ccmu.edu.cn.
Yifan ZhangDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. zyfemily@163.com.
Yifan WangDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. wyf19950527@126.com.
Xiaoli WangDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. 15801371767@163.com.
Qi SunDepartment of Pharmaceutics, School of Pharmaceutical Sciences, Capital Medical University, Beijing 100069, China. 15810587759@163.com.
Capital Medical University · CN

Funding

Beijing natural Science Foundation Program and Scientific Research Key Program of Beijing Municipal Commission of Education KM201810025019National Natural Science Foundation of China 81502688
6 · The paper itself

Abstract

A successful siRNA delivery system is dependent on the development of a good siRNA carrier. Graphene oxide (GO) has gained great attention as a promising nanocarrier in recent years. It has been reported that GO could be used to deliver a series of drugs including synthetic compounds, proteins, antibodies, and genes. Our previous research indicated that functionalized GO could deliver siRNA into tumor cells and induce a gene silencing effect, to follow up the research, in this research, GO-R8/cRGDfV(GRcR) was designed and prepared for

Indexed as

Gene Transfer TechniquesAnimalsCalorimetry, Differential ScanningCell DeathCell MovementCell ProliferationCell SurvivalGene SilencingGraphiteHeLa CellsHumansMice, NudeNeoplasmsNeovascularization, PhysiologicOligopeptidesParticle Sizecyclo(arginyl-glycyl-aspartyl-phenylalanyl-valyl)graphene oxideGraphiteoctaarginineOligopeptidesPeptides, CyclicRNA, MessengerRNA, Small InterferingVascular Endothelial Growth Factor Agene deliverygraphene oxide (GO)nanocarriersmall interfering RNAVEGF-siRNA

Identifiers

PMID30336549
PMCPMC6214041
OpenAlexW2896246032

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.