Evidence map›Paper›PMID 30336196›Full record

ReviewNeuroscience letters2018

Temperature-dependent behaviors of parasitic helminths.

Astra S Bryant, Elissa A Hallem

Abstract readReview
In one paragraph

Review in Neuroscience letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.0field-weighted citation impact, top 22% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 28 citations in OpenAlex.

  1. Article
  2. Review
  3. Review
  4. Article
  5. Review
  6. Article
  7. Article
  8. Article
  9. Article
  10. Article
  11. Article
  12. Thermosensory behaviors of the free-living life stages ofbioRxiv : the preprint server for biology · 2024
    Article
  13. Invade or die: behaviours and biochemical mechanisms that drive skin penetration inPhilosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  14. Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2024
    Review
  15. Article
  16. Review
  17. Chemosensory mechanisms of host seeking and infectivity in skin-penetrating nematodes.Proceedings of the National Academy of Sciences of the United States of America · 2020
    Article
  18. Review
  19. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Astra S BryantDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA.
Elissa A HallemDepartment of Microbiology, Immunology, and Molecular Genetics, University of California, Los Angeles, Los Angeles, CA, 90095, USA. Electronic address: ehallem@ucla.edu.
University of California, Los Angeles · US

Funding

Training Program in Neural MicrocircuitsT32NS058280 · NINDS · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI FELDMAN, JACK L · 2007 to 2017
$2.4M
The neural basis of odor-driven behavior in skin-penetrating parasitic nematodes.DP2DC014596 · NIDCD · UNIVERSITY OF CALIFORNIA LOS ANGELES · PI HALLEM, ELISSA ANYON · 2014 to 2014
$2.3M
NIDCD NIH HHS DP2 DC014596NINDS NIH HHS T32 NS058280
6 · The paper itself

Abstract

Parasitic helminth infections are the most common source of neglected tropical disease among impoverished global communities. Many helminths infect their hosts via an active, sensory-driven process in which environmentally motile infective larvae position themselves near potential hosts. For these helminths, host seeking and host invasion can be divided into several discrete behaviors that are regulated by both host-emitted and environmental sensory cues, including heat. Thermosensation is a critical sensory modality for helminths that infect warm-blooded hosts, driving multiple behaviors necessary for host seeking and host invasion. Furthermore, thermosensory cues influence the host-seeking behaviors of both helminths that parasitize endothermic hosts and helminths that parasitize insect hosts. Here, we discuss the role of thermosensation in guiding the host-seeking and host-infection behaviors of a diverse group of helminths, including mammalian-parasitic nematodes, entomopathogenic nematodes, and schistosomes. We also discuss the neural circuitry and molecular pathways that underlie thermosensory responses in these species.

Indexed as

TemperatureAnimalsBehaviorChemotaxisHelminthsHumansOdorantsThermosensingHost seekingParasitic helminthParasitic nematodeSchistosomesSensory behaviorStrongyloidesThermosensation

Identifiers

PMID30336196
PMCPMC6240462
OpenAlexW2896946825

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.