Evidence map›Paper›PMID 30336038›Full record

ArticleThe journal of physical chemistry letters2018

Electronic State Mixing Controls the Photoreactivity of a Rhodopsin with all- trans Chromophore Analogues.

Madushanka Manathunga, Xuchun Yang, Massimo Olivucci

Open access · greenAbstract read
In one paragraph

Article in The journal of physical chemistry letters, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 24 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Deciphering Methylation Effects on SThe journal of physical chemistry. A · 2023
    Article
  6. Article
  7. Theoretical Study of the Photoisomerization Mechanism of All-The journal of physical chemistry. A · 2021
    Article
  8. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 2 institutions in 3 countries.

Madushanka ManathungaDepartment of Chemistry , Bowling Green State University , Bowling Green , Ohio 43403 , United States.ORCID http://orcid.org/0000-0002-3594-8112
Xuchun YangDepartment of Chemistry , Bowling Green State University , Bowling Green , Ohio 43403 , United States.
Massimo OlivucciDepartment of Chemistry , Bowling Green State University , Bowling Green , Ohio 43403 , United States.ORCID http://orcid.org/0000-0002-8247-209X
Bowling Green State University · USUniversity of Siena · IT

Funding

Computational Design of Highly Fluorescent RhodopsinsR15GM126627 · NIGMS · BOWLING GREEN STATE UNIVERSITY · PI OLIVUCCI, MASSIMO · 2018 to 2018
$337k
NIGMS NIH HHS R15 GM126627
6 · The paper itself

Abstract

Rhodopsins hosting synthetic retinal protonated Schiff base analogues are important for developing tools for optogenetics and high-resolution imaging. The ideal spectroscopic properties of such analogues include long-wavelength absorption/emission and fast/hindered photoisomerization. While the former may be achieved, for instance, by elongating the chromophore π-system, the latter requires a detailed understanding of the substituent effects (i.e., steric or electronic) on the chromophore light-induced dynamics. In the present letter we compare the results of quantum mechanics/molecular mechanics excited-state trajectories of native and analogue-hosting microbial rhodopsins from the eubacterium Anabaena. The results uncover a relationship between the nature of the substituent on the analogue (i.e., electron-donating (a Me group) or electron-withdrawing (a CF

Identifiers

PMID30336038
PMCPMC6261349
OpenAlexW2896817369

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.