Evidence map›Paper›PMID 30336003›Full record

ArticleJournal of the American Chemical Society2018

Magnetic Targeting of Nanotheranostics Enhances Cerenkov Radiation-Induced Photodynamic Therapy.

Dalong Ni, Carolina A Ferreira, Todd E Barnhart, Virginia Quach, Bo Yu, Dawei Jiang, Weijun Wei, Huisheng Liu, Jonathan W Engle, Ping Hu and 1 more

Abstract read
In one paragraph

Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 57 papers.

0numbers the graph read from it
0cells of the map it votes in
57citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

57 citing papers in PubMed.

  1. Review
  2. Review
  3. Review
  4. Article
  5. Article
  6. Review
  7. Phototherapy in cancer treatment: strategies and challenges.Signal transduction and targeted therapy · 2025
    Review
  8. Review
  9. Review
  10. Article
  11. Review
  12. Article
  13. Review
  14. Review
  15. Article
  16. Review
  17. New Types of Magnetic Nanoparticles for Stimuli-Responsive Theranostic Nanoplatforms.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2024
    Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Dalong NiDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.ORCID 0000-0001-6679-5414
Carolina A FerreiraDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Todd E BarnhartDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Virginia QuachDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Bo YuDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Dawei JiangDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.ORCID 0000-0002-4072-0075
Weijun WeiDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Huisheng LiuInterdisciplinary Innovation Institute of Medicine & Engineering, Beijing Advanced Innovation Center for Big Data-Based Precision Medicine, School of Biological Science and Medical Engineering , Beihang University , Beijing 100191 , China.
Jonathan W EngleDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.
Ping HuState Key Laboratory of High Performance Ceramics and Superfine Microstructures, Shanghai Institute of Ceramics , Chinese Academy of Sciences , Shanghai 200050 , China.
Weibo CaiDepartments of Radiology and Medical Physics , University of Wisconsin-Madison , Wisconsin 53705 , United States.ORCID 0000-0003-4641-0833

Funding

UW COMPREHENSIVE CANCER CENTER SUPPORTP30CA014520 · NCI · UNIVERSITY OF WISCONSIN-MADISON · PI AMY TRENTHAM-DIETZ · 1985 to 2026
$142.6M
NCI NIH HHS P30 CA014520
6 · The paper itself

Abstract

The interaction between radionuclides and nanomaterials could generate Cerenkov radiation (CR) for CR-induced photodynamic therapy (PDT) without requirement of external light excitation. However, the relatively weak CR interaction leaves clinicians uncertain about the benefits of this new type of PDT. Therefore, a novel strategy to amplify the therapeutic effect of CR-induced PDT is imminently required to overcome the disadvantages of traditional nanoparticulate PDT such as tissue penetration limitation, external light dependence, and low tumor accumulation of photosensitizers. Herein, magnetic nanoparticles (MNPs) with

Indexed as

PhotochemotherapyAnimalsCell SurvivalFemaleFluorescence Resonance Energy TransferHumansMagnetite NanoparticlesMammary Neoplasms, ExperimentalMiceMice, Inbred BALB CPorphyrinsPositron-Emission TomographyRadioisotopesTumor Cells, CulturedZirconiumMagnetite NanoparticlesPorphyrinsRadioisotopesZirconiumZirconium-89

Identifiers

PMID30336003
PMCPMC6310174

What OpenQuestion holds

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Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.