Evidence map›Paper›PMID 30335840›Full record

Observational studyPloS one2018

The course of neuropsychiatric symptoms in nursing home residents from admission to 30-month follow-up.

Anne-Sofie Helvik, Geir Selbæk, Jūratė Šaltytė Benth, Irene Røen, Sverre Bergh

Erratum issuedAbstract readObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. An erratum has been issued. Cited by 29 papers.

0numbers the graph read from it
0cells of the map it votes in
29citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

29 citing papers in PubMed.

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  7. Physical activity, neuropsychiatric symptoms, and physical function in nursing home residents: the HUNT 70+ study.European review of aging and physical activity : official journal of the European Group for Research into Elderly and Physical Activity · 2025
    Article
  8. Neuropsychiatric Symptom Profile in Alzheimer's Disease and Their Relationship With Functional Decline.The American journal of geriatric psychiatry : official journal of the American Association for Geriatric Psychiatry · 2024
    Article
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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

5 authors.

Anne-Sofie HelvikGeneral Practice Research Unit, Department of Public Health and Nursing, Faculty of Medicine and health Sciences, Norwegian University of Science and Technology (NTNU), Trondheim, Norway.ORCID 0000-0002-2632-0913
Geir SelbækNorwegian National Advisory Unit on Ageing and Health, Vestfold Health Trust, Tønsberg, Norway.
Jūratė Šaltytė BenthCentre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway.
Irene RøenCentre for Old Age Psychiatric Research, Innlandet Hospital Trust, Ottestad, Norway.
Sverre BerghNorwegian National Advisory Unit on Ageing and Health, Vestfold Health Trust, Tønsberg, Norway.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimThe aim of this study was to describe the prevalence and persistence of clinically significant neuropsychiatric symptoms (NPS) in nursing home residents with dementia, and to study the association between severity of dementia and specific neuropsychiatric sub-syndromes over time.

methodsIn total, 583 residents with dementia were included at admission to a nursing home and followed with biannual assessments until death, or to 30-month follow-up. At the end of the 30-month follow-up, 305 participants had died and 57 had left the study for other reasons, leaving 221 residents in the study. We collected data on demographics, cognition, severity of dementia, NPS, personal activities of daily living (P-ADL), physical health, medication and type of nursing home unit. NPS was assessed using the Neuropsychiatric Inventory (NPI), the Nursing Home version.

resultsThe prevalence and persistence at two consecutive time-points of clinically significant NPS was high during the study period. The mean NPI agitation sub-syndrome score increased during the study period, while the NPI affective and psychosis sub-syndrome scores remained unchanged. More severe dementia was associated with higher NPI agitation, psychosis and affective sub-syndrome scores. The association remained unchanged over time for agitation and psychosis. For the NPI affective sub-syndrome, the association was stronger at the beginning, and declined towards the end of the study period.

conclusionThe findings of high prevalence and persistence at two consecutive time points of clinically significant NPS over time, and the associations between severity of dementia and NPI sub-syndromes shed light on the burden and care needs of nursing home residents with dementia after admission to nursing home care. This information is of interest to health care planners and providers to enable them to increase the quality of care for nursing home residents.

Indexed as

Activities of Daily LivingAgedAged, 80 and overDementiaFemaleFollow-Up StudiesHospitalizationHumansLongitudinal StudiesMaleNeuropsychological TestsNursing HomesPrevalencePsychomotor AgitationPsychotic DisordersSeverity of Illness Index

Identifiers

PMID30335840
PMCPMC6193723

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.