Evidence map›Paper›PMID 30335769›Full record

ArticlePloS one2018

Reassessing pregnancy intention and its relation to maternal, perinatal and neonatal outcomes in a low-income setting: A cohort study.

Jennifer Anne Hall, Geraldine Barrett, Andrew Copas, Tambosi Phiri, Address Malata, Judith Stephenson

Abstract read
In one paragraph

Article in PloS one, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 2 syntheses or guidelines pooled it.

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  19. Adverse Childhood Experiences and Pregnancy Intentions among Pregnant Women Seeking Prenatal Care.Women's health issues : official publication of the Jacobs Institute of Women's Health
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Jennifer Anne HallResearch Department of Reproductive Health, UCL Institute for Women's Health, London, United Kingdom.ORCID 0000-0002-2084-9568
Geraldine BarrettResearch Department of Reproductive Health, UCL Institute for Women's Health, London, United Kingdom.
Andrew CopasDepartment of Infection & Population Health, UCL Institute of Epidemiology and Health Care, London, United Kingdom.
Tambosi PhiriMaiMwana Project, Mchinji, Malawi.
Address MalataMalawi University of Science and Technology, Zomba, Malawi.
Judith StephensonResearch Department of Reproductive Health, UCL Institute for Women's Health, London, United Kingdom.

Funding

Wellcome Trust 097268/Z/11/Z
6 · The paper itself

Abstract

backgroundIt is unclear whether unintended pregnancies are associated with adverse outcomes. Data are predominantly from high-income countries and have methodological limitations, calling the findings into question. This research was designed to overcome these limitations and assess the relationships between pregnancy intention and miscarriage, stillbirth, low birthweight, neonatal death and postnatal depression in a low-income country.

methodsThe pregnancy intention of 4,244 pregnant women in Mchinji District, Malawi, was measured using the validated Chichewa version of the London Measure of Unplanned Pregnancy (LMUP). Women were re-interviewed postnatally to assess pregnancy outcome. Postnatal depression was assessed using the WHO's Self-Reporting Questionnaire. Multivariable regressions were conducted, with the choice of confounders informed by a pre-existing conceptual epidemiological hierarchy.

resultsPlanned pregnancies are associated with a reduced risk of any (adjusted RR 0.90 [95%CI 0.86, 0.95]) or high symptoms of depression (adjusted RR 0.76 [95%CI 0.63, 0.91]) compared to unplanned pregnancies in rural Malawi. There was no relationship between pregnancy intention and the composite measure of miscarriage, stillbirth, low birthweight and neonatal death. There was some evidence that greater pregnancy intention was associated with reduced adjusted risk of stillbirth (0·93 [95%CI 0·87, 1·00]).

conclusionOur study is the first to use a psychometrically valid measure of pregnancy intention, and to do so antenatally. As pregnancy intention increases, the risk of postnatal depression and, possibly, stillbirth decreases. This suggests a new, clinical use for the LMUP; identifying women antenatally who are at risk of these adverse pregnancy outcomes.

Indexed as

Abortion, SpontaneousAdolescentCohort StudiesDepression, PostpartumFemaleHumansInfant, Low Birth WeightInfant, NewbornMalawiMalePerinatal DeathPovertyPregnancyPregnancy OutcomePregnancy, UnplannedSelf Report

Identifiers

PMID30335769
PMCPMC6193645

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.