ArticlePain2019
Long-term outcomes of adolescents with juvenile-onset fibromyalgia into adulthood and impact of depressive symptoms on functioning over time.
Article in Pain, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 34 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
34 citing papers in PubMed, 74 citations in OpenAlex.
- Internet-Based Behavioural Therapy for Adolescents With Temporomandibular Disorder Pain: A Feasibility Multicenter Randomised Controlled Trial.Journal of oral rehabilitation · 2025Trial
- Clinical Characterization of Juvenile Fibromyalgia in a Multicenter Cohort of Adolescents Enrolled in a Randomized Clinical Trial.Arthritis care & research · 2023Trial
- Effectiveness of a Psychosocial Aftercare Program for Youth Aged 8 to 17 Years With Severe Chronic Pain: A Randomized Clinical Trial.JAMA network open · 2021Trial
- Trial
- "Too little, too late": a qualitative exploration of the unique pain management unmet needs of young adults with migraine.Frontiers in pain research (Lausanne, Switzerland) · 2026Article
- The relationships between proinflammatory cytokines and depressive symptoms in adolescents with chronic pain.Pain reports · 2025Article
- Patient subtyping in juvenile fibromyalgia: the role of multisensory hypersensitivity and neurophysiological correlates.Journal of pediatric psychology · 2025Article
- Coping in youth living with chronic pain: A systematic review of qualitative evidence.Canadian journal of pain = Revue canadienne de la douleur · 2025Article
- Article
- Neurophysiology of Resilience in Juvenile Fibromyalgia.medRxiv : the preprint server for health sciences · 2024Article
- Reduced Cortico-Cortical Resting-State Connectivity in Sensory Systems Related to Bodily Pain in Juvenile Fibromyalgia.Arthritis & rheumatology (Hoboken, N.J.) · 2024Article
- Beliefs About Pain in Pediatric Inflammatory and Noninflammatory Chronic Musculoskeletal Conditions: A Scoping Review.Journal of pediatric psychology · 2023Article
- Pain-Related Stigma and Its Associations With Clinical and Experimental Pain Severity in Youth With Chronic Musculoskeletal Pain Conditions.Journal of pediatric psychology · 2023Article
- Family structure and multisite musculoskeletal pain in adolescence: a Northern Finland Birth Cohort 1986 study.BMC musculoskeletal disorders · 2023Article
- Predicting the Need for Transition from Pediatric to Adult Pain Services: A Retrospective, Longitudinal Study Using the Electronic Persistent Pain Outcome Collaboration (ePPOC) Databases.Children (Basel, Switzerland) · 2023Article
- The complexities of the sleep-pain relationship in adolescents: A critical review.Sleep medicine reviews · 2023Review
- Prevention is better than cure: why early interventions for insomnia and chronic pain during adolescence should be a priority.Frontiers in psychology · 2023Article
- Signature for Pain Recovery IN Teens (SPRINT): protocol for a multisite prospective signature study in chronic musculoskeletal pain.BMJ open · 2022Article
- A Scoping Review and Proposed Framework for Coping in Youth With a History of Psychological Trauma and Chronic Pain.Journal of pediatric psychology · 2022Article
- Sleep Health Assessment and Treatment in Children and Adolescents with Chronic Pain: State of the Art and Future Directions.Journal of clinical medicine · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
14 authors at 6 institutions in 1 country.
Funding
Abstract
Juvenile-onset fibromyalgia (JFM) is typically diagnosed in adolescence and characterized by widespread pain and marked functional impairment. The long-term impact of JFM into adulthood is poorly understood. The objectives of this study were to describe physical and psychosocial outcomes of youth diagnosed with JFM in early adulthood (∼8-year follow-up), examine longitudinal trajectories of pain and depressive symptoms from adolescence to young adulthood, and examine the impact of pain and depressive symptoms on physical functioning over time. Participants were 97 youth with JFM enrolled in a prospective longitudinal study in which pain symptoms, and physical and psychosocial functioning were assessed at 4 time points over approximately 8 years. At the time 4 follow-up (Mage = 24.2 years), the majority continued to suffer from pain and impairment in physical, social, and psychological domains. However, trajectories of pain and emotional symptoms showed varying patterns. Longitudinal analysis using growth mixture modeling revealed 2 pain trajectories (Steady Improvement and Rapid Rebounding Improvement), whereas depressive symptoms followed 3 distinct trajectories (Low-Stable, Improving, and Worsening). Membership in the Worsening Depressive symptoms group was associated with poorer physical functioning over time (P < 0.001) compared with the Low-Stable and Improving groups. This study offers evidence that although JFM symptoms persist for most individuals, pain severity tends to decrease over time. However, depressive symptoms follow distinct trajectories that indicate subgroups of JFM. In particular, JFM patients with worsening depressive symptoms showed decreasing physical functioning and may require more intensive and consistent intervention to prevent long-term disability.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.