ArticleJournal of the American Chemical Society2018
Catalysis of Template-Directed Nonenzymatic RNA Copying by Iron(II).
Article in Journal of the American Chemical Society, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
16 citing papers in PubMed.
- MgJournal of the American Chemical Society · 2026Article
- Influence of Phosphate Activation Chemistry on the Selection of the Primordial Genetic Alphabet.Journal of the American Chemical Society · 2026Article
- Efficient Assembly of Functional RNA byJournal of the American Chemical Society · 2025Article
- Significant impacts of metal ions from ancient oceans on nucleoside phosphorylation.BMC chemistry · 2025Article
- The Pigment World: Life's Origins as Photon-Dissipating Pigments.Life (Basel, Switzerland) · 2024Article
- Catalytic Metal Ion-Substrate Coordination during Nonenzymatic RNA Primer Extension.Journal of the American Chemical Society · 2024Article
- Natural soda lakes provide compatible conditions for RNA and membrane function that could have enabled the origin of life.PNAS nexus · 2024Article
- The Non-Equilibrium Thermodynamics of Natural Selection: From Molecules to the Biosphere.Entropy (Basel, Switzerland) · 2023Article
- Growth, replication and division enable evolution of coacervate protocells.Chemical communications (Cambridge, England) · 2022Review
- Sequencing the origins of life.BBA advances · 2022Review
- Evolution towards increasing complexity through functional diversification in a protocell model of the RNA world.Proceedings. Biological sciences · 2021Article
- Origin of Life on Mars: Suitability and Opportunities.Life (Basel, Switzerland) · 2021Article
- In search of the RNA world on Mars.Geobiology · 2021Article
- Article
- Prebiotic amino acids bind to and stabilize prebiotic fatty acid membranes.Proceedings of the National Academy of Sciences of the United States of America · 2019Article
- Nonenzymatic Template-Directed Synthesis of Mixed-Sequence 3'-NP-DNA up to 25 Nucleotides Long Inside Model Protocells.Journal of the American Chemical Society · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The study of nonenzymatic template-directed RNA copying is the experimental basis for the search for chemistry and reaction conditions consistent with prebiotic RNA replication. The most effective model systems for RNA copying have to date required a high concentration of Mg
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.