Evidence map›Paper›PMID 30335138›Full record

ArticleNucleic acids research2019

The mouse Gene Expression Database (GXD): 2019 update.

Constance M Smith, Terry F Hayamizu, Jacqueline H Finger, Susan M Bello, Ingeborg J McCright, Jingxia Xu, Richard M Baldarelli, Jonathan S Beal, Jeffrey Campbell, Lori E Corbani and 9 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Nucleic acids research, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 73 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
73citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

73 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Article
  3. Article
  4. Incomplete lineage sorting shaped mixed traits during a colobine primate radiation.Proceedings of the National Academy of Sciences of the United States of America · 2026
    Article
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13 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

19 authors.

Constance M SmithThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Terry F HayamizuThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Jacqueline H FingerThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Susan M BelloThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Ingeborg J McCrightThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Jingxia XuThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Richard M BaldarelliThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Jonathan S BealThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Jeffrey CampbellThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Lori E CorbaniThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Pete J FrostThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Jill R LewisThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Sharon C GiannattoThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Dave MiersThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
David R ShawThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
James A KadinThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Joel E RichardsonThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Cynthia L SmithThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.
Martin RingwaldThe Jackson Laboratory, 600 Main Street, Bar Harbor, ME 04609, USA.

Funding

Technical DevelopmentP41HD062499 · NICHD · JACKSON LABORATORY · PI MARTIN RINGWALD · 2011 to 2026
$37.3M
NICHD NIH HHS P41 HD062499
6 · The paper itself

Abstract

The mouse Gene Expression Database (GXD) is an extensive, well-curated community resource freely available at www.informatics.jax.org/expression.shtml. Covering all developmental stages, GXD includes data from RNA in situ hybridization, immunohistochemistry, RT-PCR, northern blot and western blot experiments in wild-type and mutant mice. GXD's gene expression information is integrated with the other data in Mouse Genome Informatics and interconnected with other databases, placing these data in the larger biological and biomedical context. Since the last report, the ability of GXD to provide insights into the molecular mechanisms of development and disease has been greatly enhanced by the addition of new data and by the implementation of new web features. These include: improvements to the Differential Gene Expression Data Search, facilitating searches for genes that have been shown to be exclusively expressed in a specified structure and/or developmental stage; an enhanced anatomy browser that now provides access to expression data and phenotype data for a given anatomical structure; direct access to the wild-type gene expression data for the tissues affected in a specific mutant; and a comparison matrix that juxtaposes tissues where a gene is normally expressed against tissues, where mutations in that gene cause abnormalities.

Indexed as

Databases, GeneticAnimalsGenomeInternetMiceTranscriptomeUser-Computer Interface

Identifiers

PMID30335138
PMCPMC6324054

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.