SynthesisMedicine2018
Effect of white-coat hypertension on arterial stiffness: A meta-analysis.
Synthesis in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 21 citations in OpenAlex.
- Masked and white coat hypertension, the double trouble of large arteries: A systematic review and meta-analysis.Journal of clinical hypertension (Greenwich, Conn.) · 2020Pooled it
- Home Blood Pressure Phenotypes and Cardiovascular Remodeling in Hemodialysis.Kidney international reports · 2026Article
- Interaction between white coat effect and hypertension on arterial stiffness.Journal of hypertension · 2026Article
- Hypertension and Postoperative Outcomes: A Retrospective Cohort Study.Anesthesiology research and practice · 2026Article
- Vascular phenotypes in early hypertension.Journal of human hypertension · 2023Article
- Leveraging the potential of machine learning for assessing vascular ageing: state-of-the-art and future research.European heart journal. Digital health · 2021Article
- Effects of white-coat, masked and sustained hypertension on coronary artery stenosis and cardiac arrhythmia.Hypertension research : official journal of the Japanese Society of Hypertension · 2020Observational
- Impact of hypertension phenotypes on the office and 24-h pulse wave velocity and augmentation index in individuals with or without antihypertensive medication use.Hypertension research : official journal of the Japanese Society of Hypertension · 2019Observational
- Characteristics of Gut Microbiota in Patients with Hypertension and/or Hyperlipidemia: A Cross-Sectional Study on Rural Residents in Xinxiang County, Henan Province.Microorganisms · 2019Article
- Association of thyroid function with white coat hypertension and sustained hypertension.Journal of clinical hypertension (Greenwich, Conn.) · 2019Observational
- Complications of White-coat Hypertension Compared to a Normotensive and Hypertensive Population.Heart views : the official journal of the Gulf Heart AssociationArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
4 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWhite-coat hypertension (WCH) is a debatable risk factor of cardio-cerebrovascular diseases and the current study results on the association between WCH and arterial stiffness are inconsistent. The aim was to investigate the effect of WCH on arterial stiffness using meta-analysis.
methodsBased on prespecified search strategies and inclusion criteria, Medline, Embase, Web Of Science, Cochrane Library, and BioSciences Information Service Preview databases were reviewed. A total of 20 studies involving 1538 WCH patients and 3582 normotensives (NT) were included. Literatures were screened for data extraction and quality assessment. Overall analysis and subgroup analysis were conducted in RevMan version 5.3 and Stata version 14.0 software.
resultsOverall analysis showed that carotid-femoral pulse wave velocity (cf-PWV) was significantly higher in WCH group than in the NT group (P < .00001, 95% CI: 0.79-3.26). Subgroup analysis showed that in adults, cf-PWV was significantly higher in the WCH patients than in the NT subjects (P<.001, 95% CI: 0.46-0.87), while in juveniles, cf-PWV was comparable between the WCH group and the NT group (P = .25, 95% CI: -0.39 to 0.61).
conclusionThis meta-analysis showed that WCH may increase arterial stiffness in adult population.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.