ArticleMedicine2018
Detection of uric acid crystal deposition by ultrasonography and dual-energy computed tomography: A cross-sectional study in patients with clinically diagnosed gout.
Article in Medicine, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 14 papers, 1 of them a synthesis that pooled it.
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Who cites it
14 citing papers in PubMed, 1 synthesis or guideline pooled it, 32 citations in OpenAlex.
- Clinical utility of Dual Energy Computed Tomography in gout: current concepts and applications.Acta bio-medica : Atenei Parmensis · 2020Pooled it
- The comprehensive role of dual-energy CT in gout as an advanced diagnostic innovation.Skeletal radiology · 2025Review
- Ultrasound Features in Gout: An Overview.Medical sciences (Basel, Switzerland) · 2024Review
- Imaging comparative analysis of familial and sporadic gout in Chinese men by multijoint ultrasonography.Frontiers in medicine · 2024Article
- Influence of contrast medium on tophus detection using dual-energy CT: phantom study and clinical illustration.European radiology experimental · 2023Article
- [Clinical characteristics of crystal deposits in joints and tendons in patients with gout].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2021Article
- Review
- External validation of Gout-calculator performance on a cohort of acute arthritis (SYNOLACTATE) sparing distal joints such as hallux and midfoot. A cross-sectional study of 170 patients.Clinical rheumatology · 2021Article
- Gout of ankle and foot: DECT versus US for crystal detection.Clinical rheumatology · 2021Article
- [Risk factors and diagnostic value for ultrasound-detected tendon monosodium urate crystal deposition in patients with gout].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- [Analysis of risk factors influencing the detection rate of urate crystal by dual energy computed tomography].Beijing da xue xue bao. Yi xue ban = Journal of Peking University. Health sciences · 2020Article
- Efficacy and safety of fire-needle in the treatment of gouty arthritis: A protocol for systematic review and meta analysis.Medicine · 2020Article
- Diagnostic value of ultrasound versus dual-energy computed tomography in patients with different stages of acute gouty arthritis.Clinical rheumatology · 2020Article
- 1-Palmitoyl-2-Linoleoyl-3-Acetyl-rac-Glycerol (PLAG) Mitigates Monosodium Urate (MSU)-Induced Acute Gouty Inflammation in BALB/c Mice.Frontiers in immunology · 2020Article
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Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
The aim of our study was to compare the performance of ultrasonography (US) and dual-energy computed tomography (DECT) in detecting the crystal deposition at lower extremity joints in patients with gout. The correlation of imaging findings with microscopic findings was further assessed whenever aspiration is available.We recruited consecutive patients who were presented with arthritis of lower extremity from January 2012 to December 2014. All the patients underwent DECT and US scan of bilateral knees, ankles, and feet. Synovial fluid was obtained by aspiration from an acute inflammatory joint if possible.Finally, 60 patients fulfilling the 1977 gout classification criteria were included in our study. We found that US can detect significantly more patients with crystal deposition than DECT (81.7% vs 56.7%, by US and DECT, respectively, P < .001). The frequency of urate crystal deposition detected by US at MTP1, knee, and ankle joints regions was 56.7%, 63.3%, and 51.7%, respectively. The percentage of positivity of double contour sign on US was 33.3%, 48.3%, and 41.7% at the joints mentioned above, respectively. There was a good correlation between ultrasound and synovial fluid analysis in detecting crystal deposition (κ = 0.87, P = .001), while the agreement between DECT and synovial fluid analysis was just fair (κ = 0.28, P = .02).The sensitivity of US in detecting urate crystal deposition in lower extremity joints was higher than DECT. The superiority was more obvious in knee and MTP1 joints. US should be considered as the first choice of image examinations when diagnosing gout.
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