Evidence map›Paper›PMID 30334907›Full record

Observational studyPediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies2018

Duration and Time Trends in Hospital Stay for Very Preterm Infants Differ Across European Regions.

Rolf F Maier, Béatrice Blondel, Aurélie Piedvache, Bjoern Misselwitz, Stavros Petrou, Patrick Van Reempts, Francesco Franco, Henrique Barros, Janusz Gadzinowski, Klaus Boerch and 4 more

Open access · greenAbstract readMulticenter StudyObservational Study
PubMed Full text at PMC Publisher
In one paragraph

Observational study in Pediatric critical care medicine : a journal of the Society of Critical Care Medicine and the World Federation of Pediatric Intensive and Critical Care Societies, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 24 papers.

0numbers the graph read from it
0cells of the map it votes in
24citing papers in PubMed
3.7field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

24 citing papers in PubMed, 62 citations in OpenAlex.

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4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

14 authors at 9 institutions in 8 countries.

Rolf F MaierChildren's Hospital, University Hospital, Philipps University Marburg, Marburg, Germany.
Béatrice BlondelInserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in pregnancy, Paris Descartes University, Paris, France.
Aurélie PiedvacheInserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in pregnancy, Paris Descartes University, Paris, France.
Bjoern MisselwitzInstitute of Quality Assurance Hesse, Eschborn, Germany.
Stavros PetrouDivision of Health Sciences, Warwick Medical School, University of Warwick, Coventry, United Kingdom.
Patrick Van ReemptsDepartment of Neonatology, Antwerp University Hospital, University of Antwerp, Antwerp, Belgium.
Francesco FrancoRegione Lazio, Health Department, Rome, Italy.
Henrique BarrosEPIUnit, Institute of Public Health, University of Porto, Porto, Portugal.
Janusz GadzinowskiDepartment of Neonatology, Poznan University of Medical Sciences, Poznan, Poland.
Klaus BoerchDepartment of Neonatology, Hvidovre University Hospital, Hvidovre, Denmark.
Arno van HeijstDepartment of Neonatology, Radboud University Medical Center, Nijmegen, The Netherlands.
Elizabeth S DraperDepartment of Health Sciences, University of Leicester, Leicester, United Kingdom.
Jennifer ZeitlinInserm UMR 1153, Obstetrical, Perinatal and Pediatric Epidemiology Research Team (Epopé), Center for Epidemiology and Statistics Sorbonne Paris Cité, DHU Risks in pregnancy, Paris Descartes University, Paris, France.
MOSAIC and EPICE Research Groups
Philipps University of Marburg · DESorbonne Paris Cité · FRInserm · FRPoznan University of Medical Sciences · PLRadboud University Medical Center · NLUniversidade do Porto · PTUniversity of Antwerp · BEUniversity of Leicester · GBUniversity of Warwick · GB

Funding

Medical Research Council G0501681Medical Research Council G0700452
6 · The paper itself

Abstract

objectivesTo compare duration and changes over time in length of hospital stay for very preterm and extremely preterm infants in 10 European regions.

designTwo area-based cohort studies from the same regions in 2003 and 2011/2012.

settingTen regions from nine European countries. PATIENTS: Infants born between 22 + 0 and 31 + 6 weeks of gestational age and surviving to discharge (Models of Organising Access to Intensive Care for Very Preterm Births cohort in 2003, n = 4,011 and Effective Perinatal Intensive Care in Europe cohort in 2011/2012, n = 4,336).

interventionsObservational study, no intervention. MEASUREMENTS AND MAIN

resultsMaternal and infant characteristics were abstracted from medical records using a common protocol and length of stay until discharge was adjusted for case-mix using negative binomial regression. Mean length of stay was 63.6 days in 2003 and varied from 52.4 to 76.5 days across regions. In 2011/2012, mean length of stay was 63.1 days, with a narrower regional range (54.0-70.1). Low gestational age, small for gestational age, low 5-minute Apgar score, surfactant administration, any surgery, and severe neonatal morbidities increased length of stay. Infant characteristics explained some of the differences between regions and over time, but large variations remained after adjustment. In 2011/2012, mean adjusted length of stay ranged from less than 54 days in the Northern region of the United Kingdom and Wielkopolska, Poland to over 67 days in the Ile-de-France region of France and the Eastern region of the Netherlands. No systematic decrease in very preterm length of stay was observed over time after adjustment for patient case-mix.

conclusionsA better understanding of the discharge criteria and care practices that contribute to the wide differences in very preterm length of stay across European regions could inform policies to optimize discharge decisions in terms of infant outcomes and health system costs.

Indexed as

Infant, Extremely PrematureAdultCohort StudiesEuropeFemaleGestational AgeHospital MortalityHumansInfantInfant, Extremely Low Birth WeightInfant, NewbornInfant, Premature, DiseasesIntensive Care Units, NeonatalLength of StayMaleYoung Adult

Identifiers

PMID30334907
PMCPMC6282674
OpenAlexW2896543554

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.