Evidence map›Paper›PMID 30334687›Full record

ArticleJournal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism2019

Neuroprotective effects of microglial P2Y

Yuichiro Fukumoto, Kenji F Tanaka, Bijay Parajuli, Keisuke Shibata, Hideyuki Yoshioka, Kazuya Kanemaru, Christian Gachet, Kazuhiro Ikenaka, Schuichi Koizumi, Hiroyuki Kinouchi

Open access · bronzeAbstract read
In one paragraph

Article in Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 36 papers.

0numbers the graph read from it
0cells of the map it votes in
36citing papers in PubMed
3.2field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

36 citing papers in PubMed, 43 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Impact Induces Phagocytic Defect in Reactive Microglia.bioRxiv : the preprint server for biology · 2025
    Article
  5. P2Y1 receptor in Alzheimer's disease.Neural regeneration research · 2025
    Article
  6. Disease-relevant upregulation of P2YNature communications · 2024
    Article
  7. Microglial P2YNeuron · 2024
    Article
  8. Review
  9. Article
  10. Article
  11. Article
  12. Review
  13. Article
  14. Review
  15. Review
  16. Review
  17. Review
  18. Review
  19. Microglial phagocytosis and regulatory mechanisms after stroke.Journal of cerebral blood flow and metabolism : official journal of the International Society of Cerebral Blood Flow and Metabolism · 2022
    Article
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 4 institutions in 2 countries.

Yuichiro FukumotoDepartment of Neurosurgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kenji F TanakaDepartment of Neuropsychiatry, Keio University School of Medicine, Tokyo, Japan.
Bijay ParajuliDepartment of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Keisuke ShibataDepartment of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Hideyuki YoshiokaDepartment of Neurosurgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Kazuya KanemaruDepartment of Neurosurgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Christian GachetInstitut National de la Santé et de la Recherche Médicale (INSERM), Strasbourg, France.
Kazuhiro IkenakaDivision of Neurobiology and Bioinformatics, National Institute for Physiological Science, Aichi, Japan.
Schuichi KoizumiDepartment of Neuropharmacology, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
Hiroyuki KinouchiDepartment of Neurosurgery, Interdisciplinary Graduate School of Medicine, University of Yamanashi, Yamanashi, Japan.
University of Yamanashi · JPInserm · FRKeio University · JPNational Institute for Physiological Sciences · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Extracellular ATP, which is released from damaged cells after ischemia, activates P2 receptors. P2Y

Indexed as

AnimalsBrain IschemiaCell DeathGlucoseHippocampusHypoxiaMiceMice, KnockoutMicrogliaNeuronsNeuroprotective AgentsReceptors, Purinergic P2Y1GlucoseNeuroprotective AgentsReceptors, Purinergic P2Y1ATPbrain ischemiacalcium imagingmicroglianeuroprotection

Identifiers

PMID30334687
PMCPMC6827120
OpenAlexW2895992010

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.