Evidence map›Paper›PMID 30334520›Full record

ArticleThe American journal of tropical medicine and hygiene2018

Case Report: Subcutaneous Ivermectin Pharmacokinetics in Disseminated

Pamela Konecny, Christopher J Weatherall, Suman Adhikari, Johan Duflou, Veli Marjoniemi, Carel J Pretorius, Brett McWhinney

Open access · bronzeAbstract readCase Reports
In one paragraph

Article in The American journal of tropical medicine and hygiene, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 1 pooled it
0.9field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 1 synthesis or guideline pooled it, 14 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Strongyloidiasis.Nature reviews. Disease primers · 2024
    Review
  4. Article
  5. Review
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 4 institutions in 1 country.

Pamela KonecnyUniversity of New South Wales, Sydney, Australia.
Christopher J WeatherallUniversity of New South Wales, Sydney, Australia.
Suman AdhikariUniversity of New South Wales, Sydney, Australia.
Johan DuflouUniversity of Sydney, Sydney, Australia.
Veli MarjoniemiUniversity of New South Wales, Sydney, Australia.
Carel J PretoriusSchool of Biomedical Sciences, University of Queensland, Brisbane, Australia.
Brett McWhinneyPathology Queensland, Brisbane, Australia.
Queensland Health · AUSt George Hospital · AUUNSW Sydney · AUUniversity of Sydney · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Parenteral ivermectin treatment of disseminated strongyloidiasis and hyperinfection is increasing, although not licensed in humans and with limited pharmacokinetic data available. Plasma and postmortem tissue analysis in an human immunodeficiency virus (HIV)/hepatitis C virus-positive man with disseminated strongyloidiasis suggests loading subcutaneous ivermectin doses are required, from which the central nervous system is protected.

Indexed as

AdultAnimalsAntiparasitic AgentsAutopsyDiarrheaFatal OutcomeHepatitis CHIV InfectionsHumansInjections, SubcutaneousIntestinal Pseudo-ObstructionIvermectinMaleStrongyloidesStrongyloidiasisAntiparasitic AgentsIvermectin

Identifiers

PMID30334520
PMCPMC6283511
OpenAlexW2896681025

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.