Evidence map›Paper›PMID 30334478›Full record

ArticleDrug delivery2018

A novel redox/pH dual-responsive and hyaluronic acid-decorated multifunctional magnetic complex micelle for targeted gambogic acid delivery for the treatment of triple negative breast cancer.

Mang Mang Sang, Fu Lei Liu, Yang Wang, Ren Jie Luo, Xiao Xian Huan, Ling Fei Han, Zhong Tao Zhang, Feng Feng, Wei Qu, Wenyuan Liu and 1 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Drug delivery, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
5.1field-weighted citation impact, top 5% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 41 citations in OpenAlex.

  1. Review
  2. Engineered Probiotic-Powered Micro-Rod Robot Bomb for Thrombus-Penetrating Explosion.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2025
    Article
  3. Article
  4. Review
  5. Caged Polyprenylated Xanthones inDrug design, development and therapy · 2023
    Review
  6. Article
  7. Review
  8. Review
  9. Gambogic acid: A shining natural compound to nanomedicine for cancer therapeutics.Biochimica et biophysica acta. Reviews on cancer · 2020
    Review
  10. Article
  11. Gambogic Acid as a Candidate for Cancer Therapy: A Review.International journal of nanomedicine · 2020
    Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Mang Mang Sanga Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
Fu Lei Liuc Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
Yang Wanga Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
Ren Jie Luoa Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
Xiao Xian Huanc Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
Ling Fei Hana Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
Zhong Tao Zhangc Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
Feng Fengc Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
Wei Quc Department of Natural Medicinal Chemistry , China Pharmaceutical University , Nanjing , People's Republic of China.
Wenyuan Liua Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
Feng Zhenga Key Laboratory of Drug Quality Control and Pharmacovigilance, Ministry of Education , China Pharmaceutical University , Nanjing , People's Republic of China.
China Pharmaceutical University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Gambogic acid (GA) is a naturally derived potent anticancer agent with extremely poor biocompatibility. In the present study, a novel of redox/pH dual-responsive multifunctional magnetic complex micelle (sPEG/HA/CSO-SS-Hex/Fe

Indexed as

Drug CarriersHyaluronic AcidMagnetite NanoparticlesMicellesAnimalsAntineoplastic AgentsCell Line, TumorFemaleHumansHydrogen-Ion ConcentrationOxidation-ReductionRats, Sprague-DawleyTriple Negative Breast NeoplasmsXanthonesAntineoplastic AgentsDrug Carriersgambogic acidHyaluronic AcidMagnetite NanoparticlesMicellesXanthonesgambogic acidhyaluronic acidMagneticredox/pH dual-responsiveTNBC

Identifiers

PMID30334478
PMCPMC6225507
OpenAlexW2896041093

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.