Evidence map›Paper›PMID 30334159›Full record

ArticleSurgical endoscopy2019

Asthma medication usage is significantly reduced following bariatric surgery.

Alfredo D Guerron, Camila B Ortega, Hui-Jie Lee, Gerardo Davalos, Jennifer Ingram, Dana Portenier

Abstract read
In one paragraph

Article in Surgical endoscopy, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Discontinuation and reduction of asthma medications after metabolic and bariatric surgery: A systematic review and meta-analysis.Obesity reviews : an official journal of the International Association for the Study of Obesity · 2023
    Pooled it
  2. Pooled it
  3. Article
  4. Review
  5. Article
  6. Glucagon-Like Peptide 1 Receptor (Journal of asthma and allergy · 2025
    Article
  7. Review
  8. Article
  9. Bariatric Surgery in Asthma: A Narrative Review.Medicina (Kaunas, Lithuania) · 2024
    Review
  10. Weight Loss Interventions for Adults With Obesity-Related Asthma.The journal of allergy and clinical immunology. In practice · 2024
    Article
  11. Review
  12. Article
  13. Article
  14. Obesity, Inflammation, and Severe Asthma: an Update.Current allergy and asthma reports · 2021
    Review
  15. Review
  16. Review
  17. Review
  18. Article
  19. The Effects of Obesity in Asthma.Current allergy and asthma reports · 2019
    Review
  20. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Alfredo D GuerronDepartment of Surgery, Division of Metabolic and Weight Loss Surgery, Duke University Health System, 407 Crutchfield St, Durham, NC, 27704, USA. daniel.guerron@duke.edu.
Camila B OrtegaDepartment of Surgery, Division of Metabolic and Weight Loss Surgery, Duke University Health System, 407 Crutchfield St, Durham, NC, 27704, USA.
Hui-Jie LeeDepartment of Biostatistics and Bioinformatics, Duke University Medical Center, Durham, NC, USA.
Gerardo DavalosDepartment of Surgery, Division of Metabolic and Weight Loss Surgery, Duke University Health System, 407 Crutchfield St, Durham, NC, 27704, USA.
Jennifer IngramDepartment of Medicine, Division of Pulmonary, Allergy and Critical Care Medicine, Duke University Health System, Durham, NC, USA.
Dana PortenierDepartment of Surgery, Division of Metabolic and Weight Loss Surgery, Duke University Health System, 407 Crutchfield St, Durham, NC, 27704, USA.

Funding

Support for QA/QC for Prior Approval ProcessUL1TR002553 · NCATS · DUKE UNIVERSITY · PI LI, JENNIFER S, MCNAMARA, JAMES O. · 2018 to 2023
$58.5M
Mechanisms that Direct Airway Remodeling in Obese AsthmaR01HL130234 · NHLBI · DUKE UNIVERSITY · PI INGRAM, JENNIFER L. · 2017 to 2020
$2.1M
NCATS NIH HHS UL1 TR002553NHLBI NIH HHS R01 HL130234
6 · The paper itself

Abstract

introductionAsthma is an important healthcare problem affecting millions in the United States. Additionally, a large proportion of patients with asthma suffer from obesity. These patients exhibit poor asthma control and reduced therapy response, increasing utilization of healthcare resources. Pulmonary symptoms improve after bariatric surgery (BS), and we hypothesized that asthma medication usage would decrease following BS.

methodsA retrospective data analysis was performed in adult patients from a single institution's database. Patients with obesity using at least one asthma medication pre-operatively who underwent BS were studied for up to 3-years post-operation. Poisson generalized linear mixed models for repeated measures were used to evaluate the effects of time and procedure type on the number of asthma medication.

resultsBariatric patients with at least one prescribed asthma medication (mean 1.4 ± 0.6) were included (n = 751). The mean age at time of operation was 46.8 ± 11.6 years, mean weight was 295.9 ± 57 lbs, and mean body mass index (BMI) was 49 ± 8.2 kg/m

conclusionBS significantly decreases asthma medication use starting 30 days post-operation with a sustained reduction for up to 3 years.

Indexed as

Bariatric SurgeryAdultAnti-Asthmatic AgentsAsthmaBody Mass IndexFemaleHumansMaleMiddle AgedObesity, MorbidRetrospective StudiesWeight LossAnti-Asthmatic AgentsAsthmaBariatric surgeryMedicationsObesity

Identifiers

PMID30334159
PMCPMC6686182

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.