Evidence map›Paper›PMID 30334105›Full record

ArticleSupportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer2019

Physical activity and exercise during preoperative pancreatic cancer treatment.

Nathan H Parker, An Ngo-Huang, Rebecca E Lee, Daniel P O'Connor, Karen M Basen-Engquist, Maria Q B Petzel, Xuemei Wang, Lianchun Xiao, David R Fogelman, Keri L Schadler and 6 more

Registry-linked trialOpen access · greenAbstract read
In one paragraph

Article in Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05496777 (Feasibility of Supervised Home-based Exercise Prehabilitation in Patients Scheduled for Pancreatic Resection), which is not on this map. Cited by 31 papers, 4 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
31citing papers in PubMed, 4 pooled it
2.5field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05496777 nacompletednot on this mapstarted 2022, after this paper: background citation

Feasibility of Supervised Home-based Exercise Prehabilitation in Patients Scheduled for Pancreatic Resection

TypeinterventionalSponsorNicole HildebrandRan2022 to 2023Enrolled45ConditionsPreoperative Physical Exercise Training, Aerobic Capacity, Aerobic Fitness, Functional MobilityArmsHome-based prehabilitation program
3 · Its place in the literature

Who cites it

31 citing papers in PubMed, 4 syntheses or guidelines pooled it, 62 citations in OpenAlex.

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  16. A Multiomics Assessment of Preoperative Exercise in Pancreatic Cancer Survivors Receiving Neoadjuvant Therapy: A Case Series.Pathophysiology : the official journal of the International Society for Pathophysiology · 2024
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

16 authors at 5 institutions in 1 country.

Nathan H ParkerDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA. nhparker@mdanderson.org.ORCID http://orcid.org/0000-0002-8947-7942
An Ngo-HuangDepartment of Palliative, Rehabilitation and Integrative Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Rebecca E LeeCollege of Nursing and Health Innovation, Center for Health Promotion and Disease Prevention, Arizona State University, Phoenix, AZ, USA.
Daniel P O'ConnorDepartment of Health and Human Performance, University of Houston, Houston, TX, USA.
Karen M Basen-EngquistDepartment of Behavioral Science, The University of Texas MD Anderson Cancer Center, Unit 1330, CPB 3.3278, PO Box 301439, Houston, TX, 77030-1439, USA.
Maria Q B PetzelDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Xuemei WangDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Lianchun XiaoDepartment of Biostatistics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
David R FogelmanDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Keri L SchadlerDepartment of Pediatrics, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Richard J SimpsonDepartment of Nutritional Sciences, The University of Arizona Cancer Center, Phoenix, AZ, USA.
Jason B FlemingDepartment of Gastrointestinal Oncology, Moffitt Cancer Center, Tampa, FL, USA.
Jeffrey E LeeDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Gauri R VaradhacharyDepartment of Gastrointestinal Medical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Sunil K SahaiDepartment of General Internal Medicine, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
Matthew H G KatzDepartment of Surgical Oncology, The University of Texas MD Anderson Cancer Center, Houston, TX, USA.
The University of Texas MD Anderson Cancer Center · USArizona State University · USMoffitt Cancer Center · USUniversity of Arizona · USUniversity of Houston · US

Funding

Tumor Evolution and Metastasis ProgramP30CA016672 · NCI · UNIVERSITY OF TX MD ANDERSON CAN CTR · PI Scott Kopetz · 1985 to 2026
$290.8M
Cancer Prevention and Research Institute of Texas Training Grant/MD Anderson Cancer Prevention Research Training Program RP170259 (Dr. Shine Chang, Principal Investigator)National Institutes of Health/National Cancer Institute P30CA016672, Clinical Trials Support Resource and the Biostatistics Research GroupNCI NIH HHS P30 CA016672
6 · The paper itself

Abstract

purposeGuidelines recommend exercise to cancer survivors, but limited data exists regarding exercise among patients undergoing preoperative cancer treatment. We examined differences in weekly self-reported exercise and accelerometer-measured physical activity among participants in a home-based exercise program administered during preoperative treatment for pancreatic cancer.

methodsParticipants were encouraged to perform at least 60 min/week of moderate-intensity aerobic exercise and at least 60 min/week of full-body strengthening exercises concurrent with chemotherapy, chemoradiation therapy or both sequentially and received resistance equipment, program instruction, and biweekly follow-up calls to encourage adherence. Self-reported aerobic and strengthening exercise minutes were measured using daily logs, and physical activity was measured objectively using accelerometers.

resultsFifty participants (48% female, mean age 66 ± 8 years) participated for an average of 16 ± 9 preoperative weeks. Participants reported overall means of 126 ± 83 weekly minutes of aerobic exercise and 39 ± 33 weekly minutes of strengthening exercise in daily logs. Participants performed 158.7 ± 146.7 weekly minutes of accelerometer-measured moderate-to-vigorous physical activity. There were no significant differences in exercise or physical activity between treatment phases.

conclusionsThese findings suggest that it is feasible to target the entire preoperative course for exercise prescription. Although participants exceeded aerobic exercise recommendations on average, we observed low strengthening exercise adherence and wide variability in self-reported exercise and accelerometer physical activity variables. These findings suggest that additional support, including program adaptations, may be necessary to overcome barriers to exercise or improve motivation when prescribing exercise in this clinical scenario.

Indexed as

AgedExerciseFemaleHumansMalePancreatic NeoplasmsPreoperative CareAccelerometerAerobic exerciseCancer survivorshipPrehabilitationStrengthening exerciseSurgery

Identifiers

PMID30334105
PMCPMC8390123
OpenAlexW2898038255

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.