Evidence map›Paper›PMID 30333895›Full record

ArticleChemCatChem2018

Terminal Alkenes from Acrylic Acid Derivatives via Non-Oxidative Enzymatic Decarboxylation by Ferulic Acid Decarboxylases.

Godwin A Aleku, Christoph Prause, Ruth T Bradshaw-Allen, Katharina Plasch, Silvia M Glueck, Samuel S Bailey, Karl A P Payne, David A Parker, Kurt Faber, David Leys

Open access · hybridAbstract read
In one paragraph

Article in ChemCatChem, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed
5.2field-weighted citation impact, top 4% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 39 citations in OpenAlex.

  1. Robots and Minimal, Physics-Informed Features: A Hybrid Framework for Enzyme Catalysis.Advanced science (Weinheim, Baden-Wurttemberg, Germany) · 2026
    Article
  2. Enzymatic Conversion of COChemical reviews · 2023
    Review
  3. Article
  4. Article
  5. Article
  6. Review
  7. Article
  8. Structure and Mechanism ofACS catalysis · 2021
    Article
  9. Article
  10. Article
  11. Article
  12. Article
  13. Article
  14. Article
  15. Review
  16. Article
  17. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 4 countries.

Godwin A AlekuManchester Institute of Biotechnology School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN United Kingdom.ORCID 0000-0003-0969-5526
Christoph PrauseDepartment of Chemistry University of Graz Heinrichstrasse 28 8010 Graz Austria).
Ruth T Bradshaw-AllenManchester Institute of Biotechnology School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN United Kingdom.
Katharina PlaschDepartment of Chemistry University of Graz Heinrichstrasse 28 8010 Graz Austria).
Silvia M GlueckAustrian Centre of Industrial Biotechnology (ACIB) 8010 Graz Austria) c/o.
Samuel S BaileyManchester Institute of Biotechnology School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN United Kingdom.
Karl A P PayneManchester Institute of Biotechnology School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN United Kingdom.
David A ParkerInnovation/Biodomain Shell International Exploration and Production Inc. Westhollow Technology Center Houston USA.
Kurt FaberDepartment of Chemistry University of Graz Heinrichstrasse 28 8010 Graz Austria).
David LeysManchester Institute of Biotechnology School of Chemistry University of Manchester 131 Princess Street Manchester M1 7DN United Kingdom.
University of Manchester · GBUniversity of Graz · ATShell (United States) · US

Funding

Biotechnology and Biological Sciences Research Council BB/K017802/1Biotechnology and Biological Sciences Research Council BB/P000622/1European Research Council 695013
6 · The paper itself

Abstract

Fungal ferulic acid decarboxylases (FDCs) belong to the UbiD-family of enzymes and catalyse the reversible (de)carboxylation of cinnamic acid derivatives through the use of a prenylated flavin cofactor. The latter is synthesised by the flavin prenyltransferase UbiX. Herein, we demonstrate the applicability of FDC/UbiX expressing cells for both isolated enzyme and whole-cell biocatalysis. FDCs exhibit high activity with total turnover numbers (TTN) of up to 55000 and turnover frequency (TOF) of up to 370 min

Indexed as

BiocatalysisDecarboxylationFerulic acid decarboxylasePrenylated flavinTerminal alkenes

Identifiers

PMID30333895
PMCPMC6175315
OpenAlexW2809494751

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.