Evidence map›Paper›PMID 30333852›Full record

ArticleFrontiers in genetics2018

Lack of Association of a Functional Polymorphism in the Serotonin Receptor Gene With Body Mass Index and Depressive Symptoms in a Large Meta-Analysis of Population Based Studies.

Beverly H Brummett, Michael A Babyak, Abanish Singh, Elizabeth R Hauser, Rong Jiang, Kim M Huffman, William E Kraus, Svati H Shah, Ilene C Siegler, Redford B Williams

Open access · goldAbstract read
In one paragraph

Article in Frontiers in genetics, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.3field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 7 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Beverly H BrummettDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Michael A BabyakDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Abanish SinghDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Elizabeth R HauserDuke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States.
Rong JiangDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Kim M HuffmanDuke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States.
William E KrausDuke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States.
Svati H ShahDuke Molecular Physiology Institute, Duke University Medical Center, Durham, NC, United States.
Ilene C SieglerDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Redford B WilliamsDepartment of Psychiatry and Behavioral Sciences, Duke University Medical Center, Durham, NC, United States.
Duke Medical Center · USDuke University Hospital · USDurham VA Medical Center · US

Funding

The Genetics Of Biobehavioral Risk Factors For CVDP01HL036587 · NHLBI · DUKE UNIVERSITY · PI KRAUS, WILLIAM E · 1986 to 2020
$35.9M
STRESS, SEROTONIN GENE &HEALTH DISPARITIESR01AG019605 · NIA · DUKE UNIVERSITY · PI WILLIAMS, REDFORD B · 2000 to 2004
$2.6M
NHLBI NIH HHS P01 HL036587NIA NIH HHS R01 AG019605
6 · The paper itself

Abstract

The serotonin receptor 5-HTR2C is thought to be involved in the function of multiple brain structures. Consequently, the

Indexed as

body mass indexdepressive symptomsracers6318sexstress

Identifiers

PMID30333852
PMCPMC6175984
OpenAlexW2895483096

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.