ArticleScientific reports2018
A comprehensive anatomical map of the peripheral octopaminergic/tyraminergic system of Drosophila melanogaster.
Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 30 papers.
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Who cites it
30 citing papers in PubMed.
- Cellular and functional dissection of the octopaminergic and tyraminergic system in the Drosophila brain.Current biology : CB · 2026Article
- Article
- Octopamine receptors inFrontiers in molecular neuroscience · 2026Article
- What goes down may come up: regurgitative behaviors and their underlying gut-brain axes-insights from genetic models and related pathologies.Journal of comparative physiology. A, Neuroethology, sensory, neural, and behavioral physiology · 2026Review
- Two classes of amine/glutamate multi-transmitter neurons innervate Drosophila internal male reproductive organs.bioRxiv : the preprint server for biology · 2025Article
- Article
- Octopaminergic descending neurons inHeliyon · 2024Article
- Heterogeneity in the projections and excitability of tyraminergic/octopaminergic neurons that innervate theFrontiers in molecular neuroscience · 2024Article
- Hearing of malaria mosquitoes is modulated by a beta-adrenergic-like octopamine receptor which serves as insecticide target.Nature communications · 2023Article
- The matricellular protein Drosophila Cellular Communication Network Factor is required for synaptic transmission and female fertility.Genetics · 2023Article
- Precise CRISPR-Cas9-mediated mutation of a membrane trafficking domain in theCurrent research in physiology · 2023Article
- Octopamine and tyramine signalling in Aedes aegypti: Molecular characterization and insight into potential physiological roles.PloS one · 2023Article
- Ion transport peptide regulates energy intake, expenditure, and metabolic homeostasis in Drosophila.Genetics · 2022Article
- Regulation ofiScience · 2022Article
- Octopaminergic/tyraminergic Tdc2 neurons regulate biased sperm usage in female Drosophila melanogaster.Genetics · 2022Article
- Review
- Octopamine drives honeybee thermogenesis.eLife · 2022Article
- Redundant functions of the SLC5A transporters Rumpel, Bumpel, and Kumpel in ensheathing glial cells.Biology open · 2022Article
- Myogenic contraction of a somatic muscle powers rhythmic flow of hemolymph through Drosophila antennae and generates brain pulsations.The Journal of experimental biology · 2021Article
- She's got nerve: roles of octopamine in insect female reproduction.Journal of neurogenetics · 2021Review
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Authors and funding
5 authors.
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Abstract
The modulation of an animal's behavior through external sensory stimuli, previous experience and its internal state is crucial to survive in a constantly changing environment. In most insects, octopamine (OA) and its precursor tyramine (TA) modulate a variety of physiological processes and behaviors by shifting the organism from a relaxed or dormant condition to a responsive, excited and alerted state. Even though OA/TA neurons of the central brain are described on single cell level in Drosophila melanogaster, the periphery was largely omitted from anatomical studies. Given that OA/TA is involved in behaviors like feeding, flying and locomotion, which highly depend on a variety of peripheral organs, it is necessary to study the peripheral connections of these neurons to get a complete picture of the OA/TA circuitry. We here describe the anatomy of this aminergic system in relation to peripheral tissues of the entire fly. OA/TA neurons arborize onto skeletal muscles all over the body and innervate reproductive organs, the heart, the corpora allata, and sensory organs in the antennae, legs, wings and halteres underlining their relevance in modulating complex behaviors.
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