Evidence map›Paper›PMID 30333560›Full record

ArticleScientific reports2018

Replication of results from a cervical cancer genome-wide association study in Taiwanese women.

Yuh-Cheng Yang, Tzu-Yang Chang, Tze-Chien Chen, Wen-Shan Lin, Chiung-Ling Lin, Yann-Jinn Lee

Open access · goldAbstract read
In one paragraph

Article in Scientific reports, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 28% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 7 citations in OpenAlex.

  1. Alternative splicing ofScience immunology · 2023
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  2. Review
  3. TheHeliyon · 2021
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  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 3 institutions in 1 country.

Yuh-Cheng YangDepartment of Gynecology and Obstetrics, MacKay Memorial Hospital, Taipei City, Taiwan.
Tzu-Yang ChangDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.
Tze-Chien ChenDepartment of Gynecology and Obstetrics, MacKay Memorial Hospital, Taipei City, Taiwan.
Wen-Shan LinDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.
Chiung-Ling LinDepartment of Medical Research, MacKay Memorial Hospital, New Taipei City, Taiwan.
Yann-Jinn LeeDepartment of Pediatric Endocrinology, MacKay Children's Hospital, Taipei City, Taiwan. yannlee@mmh.org.tw.
Mackay Memorial Hospital · TWMackay Medical College · TWTaipei Medical University · TW

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Genetic epidemiological studies show that genetic factors contribute significantly to cervical cancer carcinogenesis. Several genome-wide association studies (GWAS) have revealed novel genetic variants associated with cervical cancer susceptibility. We aim to replicate 4 GWAS-identified single nucleotide polymorphisms (SNPs), which were associated with invasive cervical cancer in Chinese women, in a Taiwanese population. The rs13117307 C/T, rs8067378 A/G, rs4282438 G/T, and rs9277952 A/G SNPs were genotyped in 507 women with cervical squamous cell carcinoma (CSCC) and 432 age/sex matched healthy controls by using TaqMan PCR Assay. Human papillomavirus (HPV) DNA test and typing were performed in CSCC patients. Only the rs4282438 SNP was found to be significantly associated (G allele, odds ratio [OR] = 0.67, P = 1.5 × 10

Indexed as

Genetic Predisposition to DiseasePolymorphism, Single NucleotideAdultAsian PeopleCarcinoma, Squamous CellCase-Control StudiesFemaleGenetic Association StudiesHumansMiddle AgedTaiwanUterine Cervical Neoplasms

Identifiers

PMID30333560
PMCPMC6193015
OpenAlexW2898024337

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.