Evidence map›Paper›PMID 30333456›Full record

ReviewActa bio-medica : Atenei Parmensis2018

Anesthesia protocols in laboratory animals used for scientific purposes.

Luca Cicero, Salvatore Fazzotta, Vincenzo Davide Palumbo, Giovanni Cassata, Attilio Ignazio Lo Monte

Abstract readReview
In one paragraph

Review in Acta bio-medica : Atenei Parmensis, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 48 papers.

0numbers the graph read from it
0cells of the map it votes in
48citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

48 citing papers in PubMed.

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  9. Effects of metformin on gut microbiota and shortZhong nan da xue xue bao. Yi xue ban = Journal of Central South University. Medical sciences · 2025
    Article
  10. Article
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  12. An Evaluation of Cellulose Hydrogels Derived fromGels (Basel, Switzerland) · 2025
    Article
  13. Article
  14. Comparative analysis of autonomic effects of ketamine-xylazine in normotensive and hypertensive rats.Brazilian journal of medical and biological research = Revista brasileira de pesquisas medicas e biologica · 2025
    Article
  15. Antioxidant Potential ofAdvances in pharmacological and pharmaceutical sciences · 2025
    Article
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  18. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Luca CiceroIstituto Zooprofilattico Sperimentale della Sicilia "A. Mirri" Palermo. cicero.luca@libero.it.
Salvatore Fazzotta
Vincenzo Davide Palumbo
Giovanni Cassata
Attilio Ignazio Lo Monte

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundA suitable, effective and free of complications anesthetic protocol is very important in experimental studies on animal models since it could bias the outcome of a trial. To date there is no universally accepted protocol for induction, maintenance and recovery from anesthesia. The endotracheal intubation with the use of inhalation anesthesia is used very especially in the from of large size laboratory animals, because it is a secure and easy control mode. However, it is not common for small laboratory animals because of the high technical skills required.

aimThe aim of this paper is a review of the main methods of induction of anesthesia in laboratory animals. MATERIALS AND

methodsWe performed an electronic search of MEDLINE (PubMed interface), ISI Web of Science and Scopus using the keywords "anesthesia" and "animal (s)" or "protocol (s)" or "surgery", without the data or the language restriction. We consider only the most common laboratory animals (rats, mice, rabbits, pigs). We identify all the scientific articles that refer to the use of anesthetics for studies on laboratory animals in all areas: experimental surgery, CT, MRI, PET. All documents identified the search criteria are subject to review only by identifying relevant studies.

conclusionsThere is a strong need for application of existing guidelines for research on experimental animals; specific guidelines for anesthesia and euthanasia should be considered and reported in future studies to ensure comparability and quality of animal experiments.

Indexed as

Animals, LaboratoryAnesthesia, GeneralAnestheticsAnimalsEuthanasia, AnimalGuidelines as TopicIntraoperative ComplicationsIntubation, IntratrachealMammalsMonitoring, IntraoperativePreanesthetic MedicationSample SizeSpecies SpecificityAnesthetics

Identifiers

PMID30333456
PMCPMC6502126

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.