ArticleThe Journal of veterinary medical science2018
Follicle sinus complexes (FSCs) in muzzle skin as postmortem diagnostic material of rabid dogs.
Article in The Journal of veterinary medical science, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
3 citing papers in PubMed, 5 citations in OpenAlex.
- Immunohistochemical detection of virus antigen in the nasal planum of rabid dogs.The Journal of veterinary medical science · 2021Article
- Follicle-sinus complexes in muzzle skin of domestic and wild animals as diagnostic material for detection of rabies.The Journal of veterinary medical science · 2020Article
- Statistical analysis of the usefulness of follicle-sinus complexes as a novel diagnostic material for canine rabies.The Journal of veterinary medical science · 2019Article
Corrections and comments
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Authors and funding
7 authors at 3 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Recently, we reported that follicle-sinus complexes (FSCs) in the muzzle skin are useful for postmortem diagnosis of rabid dogs. Here, we compared the sensitivity and specificity of detecting the viral antigen in the brain and FSCs of 226 suspected rabid dogs, and assessed whether the FSC harbored the virus genome and particles. The viral antigen was detected in 211 of 226 samples with 100% sensitivity and specificity. Viral RNA and particles were observed in the cytoplasm of Merkel cells (MCs). These results suggest that MCs are targets of virus infection and FSCs are useful material for diagnosing rabies.
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Registered trials
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