Evidence map›Paper›PMID 30333243›Full record

ArticleJournal of the Royal Society, Interface2018

The effect of polyaspartate chain length on mediating biomimetic remineralization of collagenous tissues.

Bryan D Quan, Eli D Sone

Open access · bronzeAbstract read
In one paragraph

Article in Journal of the Royal Society, Interface, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 12 papers.

0numbers the graph read from it
0cells of the map it votes in
12citing papers in PubMed
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

12 citing papers in PubMed, 36 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
  4. Article
  5. Article
  6. Review
  7. Review
  8. Biomineralization of Collagen-Based Materials for Hard Tissue Repair.International journal of molecular sciences · 2021
    Review
  9. Mineralized DNA-collagen complex-based biomaterials for bone tissue engineering.International journal of biological macromolecules · 2020
    Article
  10. Article
  11. Review
  12. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

2 authors at 1 institution in 1 country.

Bryan D QuanInstitute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada.ORCID 0000-0002-1221-3498
Eli D SoneInstitute of Biomaterials and Biomedical Engineering, University of Toronto, Toronto, Ontario, Canada eli.sone@utoronto.ca.ORCID 0000-0001-7087-473X
University of Toronto · CA

Funding

CIHR MOP-142370
6 · The paper itself

Abstract

Formation of hydroxyapatite (HAP) within collagen fibrils, as found in bone, dentine and cementum, is thought to be mediated by proteins rich in aspartate (Asp) and glutamate such as osteopontin and bone sialoprotein, respectively. Indeed polyaspartate (pAsp), a homopolymer analogue of such proteins, has been shown to induce intrafibrillar mineralization of collagen from solutions of calcium and phosphate that are supersaturated with respect to HAP. To elucidate the role of pAsp in mineralization of collagen, we explored the effect of pAsp chain length on

Indexed as

Calcification, PhysiologicAnimalsBiomimeticsCalciumCollagenDurapatiteDynamic Light ScatteringExtracellular MatrixMicePeptidesCalciumCollagenDurapatitePeptidespolyaspartateamorphous calcium phosphatebiomineralizationcollagencrystallizationhydroxyapatitepolyaspartate

Identifiers

PMID30333243
PMCPMC6228489
OpenAlexW2897776209

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.