ArticleCancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology2019
Adult Physical Activity and Breast Cancer Risk in Women with a Family History of Breast Cancer.
Article in Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06005025 (The Effect of Counselling and Follow-up After Breast Cancer Awareness Education on Early Diagnosis and Healthy Lifestyle Behaviours), which is not on this map. Cited by 20 papers, 2 of them syntheses that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
The Effect of Counselling and Follow-up After Breast Cancer Awareness Education on Early Diagnosis and Healthy Lifestyle Behaviours: 'Reduce Risks, Increase Life Chances'
Who cites it
20 citing papers in PubMed, 2 syntheses or guidelines pooled it, 50 citations in OpenAlex.
- Non-occupational physical activity and risk of cardiovascular disease, cancer and mortality outcomes: a dose-response meta-analysis of large prospective studies.British journal of sports medicine · 2023Pooled it
- Modifiable risk factors in women at high risk of breast cancer: a systematic review.Breast cancer research : BCR · 2023Pooled it
- Real-world treatment patterns and sequencing in patients with advanced / metastatic HR+/HER2- breast cancer in Europe and the United States.Breast (Edinburgh, Scotland) · 2026Article
- Physical activity and incident cardiovascular disease in breast cancer survivors: the Pathways Study.JNCI cancer spectrum · 2025Article
- Outcomes of physical exercises on initiation, progression, and treatment of breast cancer.Cell communication and signaling : CCS · 2024Review
- Associations of pre-diagnosis physical activity with treatment tolerance and treatment efficacy in breast cancer patients with neoadjuvant chemotherapy.Breast cancer (Tokyo, Japan) · 2024Article
- Neighborhood greenness and participation in specific types of recreational physical activities in the Sister Study.Environmental research · 2024Article
- Breast cancer screening among Hispanic and non-Hispanic White women by birthplace in the Sister Study.Cancer medicine · 2022Article
- Insulin and cancer: a tangled web.The Biochemical journal · 2022Review
- Consumption of "Diabetes Risk Reduction Diet" and Odds of Breast Cancer Among Women in a Middle Eastern Country.Frontiers in nutrition · 2022Article
- Early-life exposures and age at thelarche in the Sister Study cohort.Breast cancer research : BCR · 2021Article
- Article
- Physical activity and cancer risk. Actual knowledge and possible biological mechanisms.Radiology and oncology · 2021Review
- A Review of Modifiable Risk Factors in Young Women for the Prevention of Breast Cancer.Breast cancer (Dove Medical Press) · 2021Review
- Review
- Pubertal timing and breast cancer risk in the Sister Study cohort.Breast cancer research : BCR · 2020Article
- Cellular Mechanisms of Circulating Tumor Cells During Breast Cancer Metastasis.International journal of molecular sciences · 2020Review
- Recreational Physical Activity Is Associated with Reduced Breast Cancer Risk in Adult Women at High Risk for Breast Cancer: A Cohort Study of Women Selected for Familial and Genetic Risk.Cancer research · 2020Article
- Physical Activity and Breast Cancer: Focusing on High-Risk Subgroups and Putting Recommendations in Context.Cancer research · 2020Article
- Airborne mammary carcinogens and breast cancer risk in the Sister Study.Environment international · 2019Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 2 institutions in 1 country.
Funding
Abstract
backgroundRecreational physical activity has been consistently associated with reduced breast cancer risk. Less is known about how family history of breast cancer affects the association and whether it varies by menopausal status.
methodsThe Sister Study is a cohort of 50,884 women who had a sister with breast cancer but no prior breast cancer themselves at enrollment. Women reported all recreational sport/exercise activities they participated in over the past 12 months. Hours/week and MET-hours/week of physical activity were considered in association with breast cancer risk. Hazard ratios (HR) and 95% confidence intervals (CI) were calculated with Cox regression. Extent of family history, examined as a modifier, was characterized by a Bayesian score incorporating characteristics of the family structure.
resultsDuring follow-up (average 8.4 years), 3,023 cases were diagnosed. Higher hours/week (HR
conclusionsIn women with a family history of breast cancer, physical activity was associated with reduced postmenopausal, but not premenopausal, breast cancer risk and was not modified by extent of family history. IMPACT: This was the first study to examine the association between physical activity and breast cancer risk in a large population with a family history of breast cancer.
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.