Evidence map›Paper›PMID 30333180›Full record

ArticlemSphere2018

Oral Administration of Porphyromonas gingivalis Alters the Gut Microbiome and Serum Metabolome.

Tamotsu Kato, Kyoko Yamazaki, Mayuka Nakajima, Yasuhiro Date, Jun Kikuchi, Koji Hase, Hiroshi Ohno, Kazuhisa Yamazaki

Open access · goldAbstract read
In one paragraph

Article in mSphere, 2018. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 128 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
128citing papers in PubMed, 1 pooled it
11.2field-weighted citation impact, top 1% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

128 citing papers in PubMed, 1 synthesis or guideline pooled it, 188 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Review
  4. Review
  5. Article
  6. Review
  7. Periodontitis in Patients With Severe Obesity: From the Oral and Gut Microbiota Dysregulation to the Visceral Adipose Tissue Inflammatory and Metabolic Disorders.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  8. Review
  9. Article
  10. Article
  11. International journal of molecular sciences · 2026
    Article
  12. Article
  13. Article
  14. Review
  15. Serum antibody titers againstFrontiers in oral health · 2026
    Article
  16. Frontiers in microbiology · 2026
    Article
  17. Article
  18. Journal of oral microbiology · 2026
    Article
  19. Article
  20. Article

68 more citing papers are in PubMed but not listed here.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 4 institutions in 1 country.

Tamotsu KatoLaboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Japan.
Kyoko YamazakiResearch Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Mayuka NakajimaResearch Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan.
Yasuhiro DateRIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Jun KikuchiRIKEN Center for Sustainable Resource Science, Yokohama, Japan.
Koji HaseDivision of Biochemistry, Faculty of Pharmacy, Keio University, Tokyo, Japan.
Hiroshi OhnoLaboratory for Intestinal Ecosystem, RIKEN Centre for Integrative Medical Sciences (IMS), Yokohama, Japan.
Kazuhisa YamazakiResearch Unit for Oral-Systemic Connection, Division of Oral Science for Health Promotion, Niigata University Graduate School of Medical and Dental Sciences, Niigata, Japan kaz@dent.niigata-u.ac.jp.ORCID 0000-0002-1893-4202
Niigata University · JPRIKEN Center for Integrative Medical Sciences · JPRIKEN Center for Sustainable Resource Science · JPKeio University · JP

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Periodontal disease induced by periodontopathic bacteria like

Indexed as

Administration, OralAnimalsFecesGastrointestinal MicrobiomeIntestinesMaleMetabolic DiseasesMetabolomeMiceMice, Inbred C57BLPeriodontal DiseasesPorphyromonas gingivalisRNA, Ribosomal, 16SSerumStatistics, NonparametricRNA, Ribosomal, 16Sgut microbiomemetabolismperiodontitisPorphyromonas gingivalis

Identifiers

PMID30333180
PMCPMC6193602
OpenAlexW2897474242

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.